Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3830156..3830299 Replicon chromosome
Accession NZ_CP053568
Organism Enterobacter cloacae strain MY490

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3830161..3830264 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3830156..3830299 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPB40_RS18490 (HPB40_18440) 3825316..3825555 + 240 WP_013096113.1 YebV family protein -
HPB40_RS18495 (HPB40_18445) 3825589..3826233 - 645 WP_013096112.1 protein-serine/threonine phosphatase -
HPB40_RS18500 (HPB40_18450) 3826400..3827341 + 942 WP_013096111.1 VirK/YbjX family protein -
HPB40_RS18505 (HPB40_18455) 3828131..3828979 + 849 WP_062934752.1 benzoate transporter -
- 3830156..3830299 + 144 - - Antitoxin
- 3830161..3830264 - 104 - - Toxin
HPB40_RS18510 (HPB40_18460) 3830404..3830742 - 339 WP_013096105.1 YebY family protein -
HPB40_RS18515 (HPB40_18465) 3830759..3831628 - 870 WP_013096104.1 copper homeostasis membrane protein CopD -
HPB40_RS18520 (HPB40_18470) 3831630..3832001 - 372 WP_013096103.1 CopC domain-containing protein YobA -
HPB40_RS18525 (HPB40_18475) 3832139..3832369 + 231 WP_013096102.1 DNA polymerase III subunit theta -
HPB40_RS18530 (HPB40_18480) 3832479..3833129 + 651 WP_013096101.1 carbon-nitrogen hydrolase family protein -
HPB40_RS18535 (HPB40_18485) 3833153..3833815 + 663 WP_013096100.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3809980..3895550 85570


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T156844 NZ_CP053568:c3830264-3830161 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT156844 NZ_CP053568:3830156-3830299 [Enterobacter cloacae]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References