Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 560470..561076 Replicon chromosome
Accession NZ_CP051539
Organism Helicobacter pylori strain LIM-003

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG576_RS02690 Protein ID WP_078264719.1
Coordinates 560816..561076 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG576_RS02685 Protein ID WP_078250009.1
Coordinates 560470..560835 (+) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG576_RS02650 555567..555767 - 201 WP_075650215.1 hypothetical protein -
HG576_RS02655 555764..555949 - 186 WP_001909401.1 hypothetical protein -
HG576_RS02660 556018..556269 - 252 WP_001105124.1 hypothetical protein -
HG576_RS02665 556266..556475 - 210 WP_000462384.1 hypothetical protein -
HG576_RS02670 556596..558275 - 1680 Protein_520 helicase -
HG576_RS02675 558303..559631 - 1329 WP_202139096.1 transposase -
HG576_RS02680 559668..560084 + 417 WP_000717707.1 IS200/IS605 family transposase -
HG576_RS02685 560470..560835 + 366 WP_078250009.1 hypothetical protein Antitoxin
HG576_RS02690 560816..561076 + 261 WP_078264719.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HG576_RS02695 561184..561708 - 525 WP_001135624.1 acyl-CoA thioesterase -
HG576_RS02700 561848..562702 + 855 WP_202139097.1 SDR family oxidoreductase -
HG576_RS02705 562695..563675 + 981 WP_000921454.1 iron ABC transporter permease -
HG576_RS02710 563675..564442 + 768 WP_024369459.1 ABC transporter ATP-binding protein -
HG576_RS02715 564520..565623 + 1104 WP_202139226.1 glycosyltransferase family 8 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10109.02 Da        Isoelectric Point: 9.5330

>T154401 WP_078264719.1 NZ_CP051539:560816-561076 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLKEVILRKKEPLPPPFKDHALKGVWKPYRECHIKPDVLLVYLVKDDELILLRLG
SHNELF

Download         Length: 261 bp

>T154401 NZ_CP068040:c106129-105971 [Escherichia coli]
ATGAAACTACCACGCAGCTCTCTTGTCTGGTGTGTGTTGATCGTGTGTCTCACACTGTTGATATTCACTTATCTGACACG
AAAATCGCTGTGCGAGATTCGTTACAGAGACGGATACAGGGAGGTGGCGGCTTTCATGGCTTACGAATCCGGTAAGTAG

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 14388.36 Da        Isoelectric Point: 8.9643

>AT154401 WP_078250009.1 NZ_CP051539:560470-560835 [Helicobacter pylori]
MPNTTKKDYTQYSQRQLFNLMNKKEQEIEKLKRDRAYLEKKMAKELEKKDKSFTIKLEELNKILQEINKRANDCCFGHET
PNIETQQAMRDAFNKETDLIVEDFSSYSDERKKALGVKTQS

Download         Length: 366 bp

>AT154401 NZ_CP068040:c106392-106194 [Escherichia coli]
TCATACAGATTACCCGTAAACAGCCTGAATGAGCGGGTTATTTTCAGGAAAAGTGAGTGTGGTCAGCGTGCAGGGATATG
GGCTATGATGTGCCCGGCGCTTGAGGCTTTCTGCCTCATGACGTGAAGGTGGTTTGTTGCCGTGTTGTGTGGCAGAAGGA
CAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References