154059

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 1773126..1773945 Replicon chromosome
Accession NZ_CP051427
Organism Klebsiella michiganensis strain X2-1

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag HGI13_RS08345 Protein ID WP_004110819.1
Coordinates 1773688..1773945 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A7H5A4B4
Locus tag HGI13_RS08340 Protein ID WP_004847994.1
Coordinates 1773126..1773677 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGI13_RS08325 1769347..1770255 - 909 WP_009654176.1 transcriptional regulator GcvA -
HGI13_RS08330 1770375..1771262 + 888 WP_209745270.1 DMT family transporter -
HGI13_RS27930 1771480..1772226 - 747 WP_224250388.1 class I SAM-dependent methyltransferase -
HGI13_RS27935 1772602..1773012 - 411 Protein_1662 class I SAM-dependent methyltransferase -
HGI13_RS08340 1773126..1773677 - 552 WP_004847994.1 N-acetyltransferase Antitoxin
HGI13_RS08345 1773688..1773945 - 258 WP_004110819.1 YjhX family toxin Toxin
HGI13_RS08350 1774621..1775805 + 1185 WP_182012006.1 mannonate dehydratase -
HGI13_RS08355 1775879..1777354 + 1476 WP_182409443.1 fructuronate reductase -
HGI13_RS08360 1777493..1778269 + 777 WP_004847986.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T154059 WP_004110819.1 NZ_CP051427:c1773945-1773688 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T154059 NZ_CP067307:c3001607-3001353 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20022.86 Da        Isoelectric Point: 6.4897

>AT154059 WP_004847994.1 NZ_CP051427:c1773677-1773126 [Klebsiella michiganensis]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGGLIRHGIEQLKAMGSQMVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT154059 NZ_CP067307:c3001855-3001604 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure
AlphaFold DB A0A7H5A4B4

References