Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/RelE-HTH |
| Location | 1770218..1770837 | Replicon | chromosome |
| Accession | NZ_CP051195 | ||
| Organism | Treponema sp. OMZ 803 strain BF2M | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | ABH09_RS07975 | Protein ID | WP_162664818.1 |
| Coordinates | 1770523..1770837 (-) | Length | 105 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | ABH09_RS07970 | Protein ID | WP_253713997.1 |
| Coordinates | 1770218..1770526 (-) | Length | 103 a.a. |
Genomic Context
Location: 1766661..1767347 (687 bp)
Type: Others
Protein ID: WP_253713994.1
Type: Others
Protein ID: WP_253713994.1
Location: 1767430..1768548 (1119 bp)
Type: Others
Protein ID: WP_253713995.1
Type: Others
Protein ID: WP_253713995.1
Location: 1768541..1770124 (1584 bp)
Type: Others
Protein ID: WP_253713996.1
Type: Others
Protein ID: WP_253713996.1
Location: 1771715..1773367 (1653 bp)
Type: Others
Protein ID: WP_253713998.1
Type: Others
Protein ID: WP_253713998.1
Location: 1765550..1766062 (513 bp)
Type: Others
Protein ID: WP_253713993.1
Type: Others
Protein ID: WP_253713993.1
Location: 1770218..1770526 (309 bp)
Type: Antitoxin
Protein ID: WP_253713997.1
Type: Antitoxin
Protein ID: WP_253713997.1
Location: 1770523..1770837 (315 bp)
Type: Toxin
Protein ID: WP_162664818.1
Type: Toxin
Protein ID: WP_162664818.1
Location: 1773394..1774524 (1131 bp)
Type: Others
Protein ID: WP_253713999.1
Type: Others
Protein ID: WP_253713999.1
Location: 1774694..1775272 (579 bp)
Type: Others
Protein ID: WP_253714000.1
Type: Others
Protein ID: WP_253714000.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABH09_RS07950 (ABH09_07935) | 1765550..1766062 | - | 513 | WP_253713993.1 | TIGR03546 family protein | - |
| ABH09_RS07955 (ABH09_07945) | 1766661..1767347 | + | 687 | WP_253713994.1 | outer membrane lipoprotein carrier protein LolA | - |
| ABH09_RS07960 (ABH09_07950) | 1767430..1768548 | + | 1119 | WP_253713995.1 | helix-turn-helix domain-containing protein | - |
| ABH09_RS07965 (ABH09_07955) | 1768541..1770124 | + | 1584 | WP_253713996.1 | MiaB/RimO family radical SAM methylthiotransferase | - |
| ABH09_RS07970 (ABH09_07960) | 1770218..1770526 | - | 309 | WP_253713997.1 | NadS family protein | Antitoxin |
| ABH09_RS07975 (ABH09_07965) | 1770523..1770837 | - | 315 | WP_162664818.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| ABH09_RS07985 (ABH09_07975) | 1771715..1773367 | + | 1653 | WP_253713998.1 | nucleoside kinase | - |
| ABH09_RS07990 (ABH09_07980) | 1773394..1774524 | - | 1131 | WP_253713999.1 | glycosyltransferase | - |
| ABH09_RS07995 (ABH09_07985) | 1774694..1775272 | - | 579 | WP_253714000.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 105 a.a. Molecular weight: 11961.14 Da Isoelectric Point: 10.3625
>T153759 WP_162664818.1 NZ_CP051195:c1770837-1770523 [Treponema sp. OMZ 803]
MELIETPVFKKQIDRLLDDLTYTQFKEYLVCNPLKGKLIRGGGGIRKIRWGKKNTGKSGGVRIIYFIKTDTQIYLLFAYA
KNESDNLTKKQTNMLAAFVKEVLL
MELIETPVFKKQIDRLLDDLTYTQFKEYLVCNPLKGKLIRGGGGIRKIRWGKKNTGKSGGVRIIYFIKTDTQIYLLFAYA
KNESDNLTKKQTNMLAAFVKEVLL
Download Length: 315 bp
>T153759 NZ_CP067073:c959089-958796 [Rhizobium sp. AB2/73]
GTGCCACGAGTGATCGTTACCGAAGGTGCGGCACAGGGTTTGGAGCGCTGCAGGCGATTTCTGGCGGCTAAGGCGCCGAC
TGCCGCAAGTCGGGCGGGCCGGGCTATCGAACGCCAGTTCCTGTTACTGGAATCAACGCCTCTTATTGGCCGCCCGCTTC
CGGACGACGCGCAATTGCGTGAACTGGTGATTCCCTTTGGGGACTCCGGCTACGTCGCGCTTTACCGACATGAGCCTGAT
GGCGATATCGTGTTTGTCCTCGCTTTCCGACATCAGAAAGAGGCTGGCTACTGA
GTGCCACGAGTGATCGTTACCGAAGGTGCGGCACAGGGTTTGGAGCGCTGCAGGCGATTTCTGGCGGCTAAGGCGCCGAC
TGCCGCAAGTCGGGCGGGCCGGGCTATCGAACGCCAGTTCCTGTTACTGGAATCAACGCCTCTTATTGGCCGCCCGCTTC
CGGACGACGCGCAATTGCGTGAACTGGTGATTCCCTTTGGGGACTCCGGCTACGTCGCGCTTTACCGACATGAGCCTGAT
GGCGATATCGTGTTTGTCCTCGCTTTCCGACATCAGAAAGAGGCTGGCTACTGA
Antitoxin
Download Length: 103 a.a. Molecular weight: 11438.26 Da Isoelectric Point: 7.2050
>AT153759 WP_253713997.1 NZ_CP051195:c1770526-1770218 [Treponema sp. OMZ 803]
MIGHKKMSDEMFSELIQSIKEAALIEKGEMEPARVSVIDALDIAAIRNKTHKTQEEFATMLNISIGTLRNWEQGRRKPDG
AALSLLKVVSADPQYVEKVLRT
MIGHKKMSDEMFSELIQSIKEAALIEKGEMEPARVSVIDALDIAAIRNKTHKTQEEFATMLNISIGTLRNWEQGRRKPDG
AALSLLKVVSADPQYVEKVLRT
Download Length: 309 bp
>AT153759 NZ_CP067073:c959349-959077 [Rhizobium sp. AB2/73]
ATGGCTACTTCTCTCAAGATTGATGACGAGCTAAAGAACCGAGTTCAGAACCTCGCCAGCCAAAGACGGCGCTCGGCACA
CTGGATCATCCTCGAAGCCATTCAGCAGTATGTCGAACGTGAGGAAGCGCGCGAAAACTTCAAACAGGAGGCTTTGGCAT
CCTGGGCGGCCTATCAGGAGACCGGCCGACATCTTACCGGACAGGAGGTACGCACTTGGCTGGACACCTGGGGCACCGAT
GCGGAAGAGACGGTACCTGAGTGCCACGAGTGA
ATGGCTACTTCTCTCAAGATTGATGACGAGCTAAAGAACCGAGTTCAGAACCTCGCCAGCCAAAGACGGCGCTCGGCACA
CTGGATCATCCTCGAAGCCATTCAGCAGTATGTCGAACGTGAGGAAGCGCGCGAAAACTTCAAACAGGAGGCTTTGGCAT
CCTGGGCGGCCTATCAGGAGACCGGCCGACATCTTACCGGACAGGAGGTACGCACTTGGCTGGACACCTGGGGCACCGAT
GCGGAAGAGACGGTACCTGAGTGCCACGAGTGA