Detailed information of TA system TA153550

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 3081933..3082466
• Replicon: chromosome
• Accession: NZ_CP051131
• Organism: Parasphingopyxis algicola strain JCM 31719

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HFP57_RS15275
• Protein ID: WP_176870586.1
• Coordinates: 3081933..3082205 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HFP57_RS15280
• Protein ID: WP_176870587.1
• Coordinates: 3082209..3082466 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HFP57_RS15260	3078125..3078631	+	507	WP_176870583.1	hypothetical protein	-
HFP57_RS15265	3078697..3079794	-	1098	WP_176870584.1	hypothetical protein	-
HFP57_RS15270	3079920..3081479	+	1560	WP_176870585.1	glutamine-hydrolyzing GMP synthase	-
HFP57_RS15275	3081933..3082205	-	273	WP_176870586.1	type II toxin-antitoxin system YafQ family toxin	Toxin
HFP57_RS15280	3082209..3082466	-	258	WP_176870587.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
HFP57_RS15285	3082579..3083286	+	708	WP_176870588.1	endonuclease III	-
HFP57_RS15290	3083656..3084324	+	669	WP_176870589.1	endonuclease III	-
HFP57_RS15295	3084317..3084757	+	441	WP_176870590.1	GNAT family acetyltransferase	-
HFP57_RS15300	3084789..3085022	+	234	WP_176870591.1	hypothetical protein	-
HFP57_RS15305	3085024..3086220	+	1197	WP_176870592.1	formate-dependent phosphoribosylglycinamide formyltransferase	-
HFP57_RS15310	3086222..3086581	+	360	WP_176870593.1	ArsC family reductase	-
HFP57_RS15315	3086706..3086987	+	282	WP_176870594.1	DUF427 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-88)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-83)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10321.17 Da
• Isoelectric Point: 10.7132

>T153550 WP_176870586.1 NZ_CP051131:c3082205-3081933 [Parasphingopyxis algicola]
VRAPVRSTAFKKDVKRMAKRGKKMAKLKAVIGMLLAGEPLDPRLRDHPLKGEWAGWRDLHIEPDWLLLYRMSETELLLAR
TGTHSDLFGE

Nucleotide

• Length: 273 bp

>T153550 NZ_CP066959:301308-301442 [Xanthomonas campestris pv. incanae]
ATGAAGCGTGCAATTGCATTGTTGGTACTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9177.33 Da
• Isoelectric Point: 4.2296

>AT153550 WP_176870587.1 NZ_CP051131:c3082466-3082209 [Parasphingopyxis algicola]
MSADESVRARIDGDTKEAATAALAAMGLSMSDAIRLMLRRVAEEKRLPFDVKVPNTESRAAMAELESGKSEAFDSADELF
DELGI

Nucleotide

• Length: 258 bp

>AT153550 NZ_CP066959:301079-301231 [Xanthomonas campestris pv. incanae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGATAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA