Detailed information of TA system TA153106

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 282215..282399
• Replicon: chromosome
• Accession: NZ_CP050691
• Organism: Staphylococcus aureus strain PMB196-1

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: HCU71_RS01465
• Protein ID: WP_167780361.1
• Coordinates: 282292..282399 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	282215..282275 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HCU71_RS01450	277670..277837	-	168	Protein_280	hypothetical protein	-
HCU71_RS01455	278068..279801	-	1734	WP_000486487.1	ABC transporter ATP-binding protein/permease	-
HCU71_RS01460	279826..281589	-	1764	WP_001064825.1	ABC transporter ATP-binding protein/permease	-
-	282215..282275	+	61	-	-	Antitoxin
HCU71_RS01465	282292..282399	-	108	WP_167780361.1	type I toxin-antitoxin system Fst family toxin	Toxin
HCU71_RS01470	282533..282919	-	387	WP_000779360.1	flippase GtxA	-
HCU71_RS01475	283187..284329	+	1143	WP_001176863.1	glycerate kinase	-
HCU71_RS01480	284389..285048	+	660	WP_000831298.1	membrane protein	-
HCU71_RS01485	285230..286441	+	1212	WP_001192075.1	multidrug effflux MFS transporter	-
HCU71_RS01490	286564..287037	-	474	WP_000456486.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3912.64 Da
• Isoelectric Point: 10.4997

>T153106 WP_167780361.1 NZ_CP050691:c282399-282292 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLGTRNNKKGDK

Nucleotide

• Length: 108 bp

>T153106 NZ_CP066756:c4610099-4609785 [Escherichia coli O157:H7]
ATGCAATTTACGGTATACCGCAGTCGCAGCAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGTGATTAATCGCCGTATTGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT153106 NZ_CP050691:282215-282275 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin