Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1557733..1557878 Replicon chromosome
Accession NZ_CP050360
Organism Klebsiella pneumoniae strain 47733

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1557740..1557842 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1557733..1557878 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB636_RS07920 1553264..1554697 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HB636_RS07925 1554813..1555052 + 240 WP_002911393.1 YebV family protein -
HB636_RS07930 1555150..1555341 + 192 WP_002911395.1 YebW family protein -
HB636_RS07935 1555338..1555991 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
HB636_RS07940 1556148..1557116 + 969 WP_014907334.1 VirK/YbjX family protein -
HB636_RS07945 1557221..1557364 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 1557733..1557878 + 146 - - Antitoxin
- 1557740..1557842 - 103 - - Toxin
HB636_RS07950 1558001..1558339 - 339 WP_002911404.1 YebY family protein -
HB636_RS07955 1558356..1559225 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HB636_RS07960 1559229..1559603 - 375 WP_039819395.1 CopC domain-containing protein YobA -
HB636_RS07965 1559716..1559946 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HB636_RS07970 1560025..1560684 + 660 WP_002911407.1 exodeoxyribonuclease X -
HB636_RS07975 1560688..1562748 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T152711 NZ_CP050360:c1557842-1557740 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT152711 NZ_CP050360:1557733-1557878 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References