Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1557733..1557878 | Replicon | chromosome |
| Accession | NZ_CP050360 | ||
| Organism | Klebsiella pneumoniae strain 47733 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1557740..1557842 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1557733..1557878 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HB636_RS07920 | 1553264..1554697 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| HB636_RS07925 | 1554813..1555052 | + | 240 | WP_002911393.1 | YebV family protein | - |
| HB636_RS07930 | 1555150..1555341 | + | 192 | WP_002911395.1 | YebW family protein | - |
| HB636_RS07935 | 1555338..1555991 | - | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| HB636_RS07940 | 1556148..1557116 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| HB636_RS07945 | 1557221..1557364 | + | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| - | 1557733..1557878 | + | 146 | - | - | Antitoxin |
| - | 1557740..1557842 | - | 103 | - | - | Toxin |
| HB636_RS07950 | 1558001..1558339 | - | 339 | WP_002911404.1 | YebY family protein | - |
| HB636_RS07955 | 1558356..1559225 | - | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| HB636_RS07960 | 1559229..1559603 | - | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| HB636_RS07965 | 1559716..1559946 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HB636_RS07970 | 1560025..1560684 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HB636_RS07975 | 1560688..1562748 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T152711 NZ_CP050360:c1557842-1557740 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT152711 NZ_CP050360:1557733-1557878 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT