Detailed information of TA system TA152350

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 2818019..2818770
• Replicon: chromosome
• Accession: NZ_CP050171
• Organism: Serratia fonticola strain CPSE11

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: HAP32_RS13055
• Protein ID: WP_166733819.1
• Coordinates: 2818019..2818501 (-)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: A0A3G2FKC3
• Locus tag: HAP32_RS13060
• Protein ID: WP_059199145.1
• Coordinates: 2818492..2818770 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HAP32_RS13030	2813334..2814377	+	1044	WP_021807714.1	TerC/Alx family metal homeostasis membrane protein	-
HAP32_RS13035	2814435..2815013	+	579	WP_021807715.1	tellurium resistance membrane protein TerD	-
HAP32_RS13040	2815086..2815661	+	576	WP_021807716.1	TerD family protein	-
HAP32_RS13045	2815855..2817099	+	1245	WP_166733818.1	VWA domain-containing protein	-
HAP32_RS13050	2817170..2817868	-	699	WP_037376573.1	HAD-IB family hydrolase	-
HAP32_RS13055	2818019..2818501	-	483	WP_166733819.1	GNAT family N-acetyltransferase	Toxin
HAP32_RS13060	2818492..2818770	-	279	WP_059199145.1	DUF1778 domain-containing protein	Antitoxin
HAP32_RS13065	2818989..2820023	+	1035	WP_166733820.1	YeeE/YedE family protein	-
HAP32_RS13070	2820029..2820256	+	228	WP_059199143.1	sulfurtransferase TusA family protein	-
HAP32_RS13075	2820452..2820688	+	237	WP_021807719.1	DUF4282 domain-containing protein	-
HAP32_RS13080	2820754..2821503	-	750	WP_021807720.1	NAD(P)-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (43-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-92)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 17598.53 Da
• Isoelectric Point: 10.1056

>T152350 WP_166733819.1 NZ_CP050171:c2818501-2818019 [Serratia fonticola]
MGMKAPEPLSSGHNLADFCSSEPMLNEWLRKKALKNHSAGISRVYVICTGETHRVIGYYCLATGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTKNIAQQVGVRALIVHALNEGVRNFYIKFAFSPSPEHPLMLFYPIKL

Nucleotide

• Length: 483 bp

>T152350 NZ_CP066126:3281101-3282003 [Chromobacterium rhizoryzae]
ATGAGCGCACTGGACCTGCCCGCTAACGCCGATGAAACCCTGCTCCTCAAACTGCGCCGACGCTTGCGCCAATGTTTTCC
GGAACGCCGGCTCCAGGTGAACGACCGCGTCGTCGCCTACCGCGAATGCGGCACCGGCGACGCCACCGTCGTGCTGCTGC
ACGGCATAGGCTCCACTTCGGCCAGCTGGATGGAGGTGGCCGCCGCGCTCGCCCCCCGCGCCCGCGTGCTGGCCTGGGAT
GCCCCCGGCTACGGCGACACCAGCCCCTTGCCGCAGGCCCGCCCCAAGGCAGACGACTACGCGCAGGCGCTGGAAGGCTT
TCTCAAAGCCGCCGGCGTCACCCGCTGCGCCCTGGTCGGCCATTCCCTGGGCGGACTGATGGCCGCCGCCCATGCGCGCC
GGCATCCGCAGCGGCTGGAACGGCTGCTGCTGGTCTCGCCGGCCCAAGGCTACGGCGCGGCCGATCGGCGCGCCGACGGC
GCGCGCGTCCGCGGCGAACGGCTACGCGCGCTGCACGCCCAGGGCCTGGCCCAAGTGGCGGACCAGGCGCCGGCCAGGCT
GCTCTCCGCCTCTGCCGACGCCGCCGCGCGCGCCTGGGTGCGCTGGAATATGGCCCAACTCAAGGAGGGCGGCTACGGCC
AAGCCGTCGAACTGCTGACTGGCGACGACATCGCCCGCTACGCGCCTTCGCCGCTGCCGGTGACGGTGTTCTGCGGCGAG
CGCGATCTGGCCACGCCGCCGGCGGATTGCCAGACCGTGGCCGCCGCCTTCAACGCGCCCTTCCATCTGATTCCCGGCTG
CGGCCACGCCTGTCACGTGGAGGCGCCGGCGGCGCTCGCCGACTTGCTCAGCGCCGCTCTCGCCCCGTCCCACCCCCACA
CCAAGGAAGCCCATCATGGATGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10641.12 Da
• Isoelectric Point: 4.4247

>AT152350 WP_059199145.1 NZ_CP050171:c2818770-2818492 [Serratia fonticola]
MKPETREAPINIRAKASQRDLIDMAASLLSKSRTDFMLEVACREAQDILLDQRLFILDDEQYDAFLTELDAPITAERQAR
INDLMSRKSPWE

Nucleotide

• Length: 279 bp

>AT152350 NZ_CP066126:3281996-3282814 [Chromobacterium rhizoryzae]
ATGGATGAGCAGAACCCCAACGACGCGGCCGCCCGCTATACCGTGCCGGCCCTGGAGCGCGGCCTGCGCCTGCTGGGCGA
ATTCAGCCGCGGCGAGCCCACGCTGAGCGCGCCGGAGCTGGCGCGCCGGCTGGCGCTGCCGCGCTCCACCGTGTTCCGCA
TGCTGGCCACGCTGGAACAGCTGGGCTTCATCGAACGCGCGGAAGGCGGCCGCGACTATCGGCTGGGCATCGCCGTGCTG
CGCCTGGGTTTCGAATACCTGTCCTCGCTGGAACTGACCGAACTGGGCCTGCCGGTGCTGGGCCGGCTGCGCGACCGGAT
CGGCCACGCCTGCAGCCTGGTGGTGCGCGACGGACGCTCCATCGTCTACGTCGCCAAGGTCAACCCACCGTCCTGGATCG
CCTCCAACATCAATATCGGCGCCCGGCTGCCCGCTCACGCCACCGTGTTCGGCCGCATCCTGCTGTCGGAACTGCCGCTG
GAGAAACTGCGCGAGCTGTATCCGGAAGAGCATCTGGACATCCATTCCAGCCAGACCCCGCGCAACACGCTGGAGCTGTT
CCACCTGCTGCAGCAAGACCGGGAGCGCACCTGCCTGGTGGGCGAAGGCTTCTTCGAAACCAATATCTCCACCGTGGCGG
CTCCGGTGCGCAACCACGGCGGCGCCATCATCGCCGCCATCGGCGCCACCCTCCCCATGCCCAGGCTGGAGCCCGGCCAA
GCCGATGCGCTGGCCGGCCACATCCGCGCCGCCGCCGCCGAGCTGTCCCGCGCGCTGGGCCACGCCGGCGGCGGCATGGG
CAAAGTCATCCACCTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A3G2FKC3