Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3510294..3510825 Replicon chromosome
Accession NZ_CP050139
Organism Komagataeibacter rhaeticus strain ENS 9a1a

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GWK63_RS16285 Protein ID WP_039998565.1
Coordinates 3510526..3510825 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GWK63_RS16280 Protein ID WP_202795779.1
Coordinates 3510294..3510539 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GWK63_RS16265 3505476..3506588 - 1113 WP_007397379.1 Fic family protein -
GWK63_RS16270 3507067..3508602 + 1536 WP_139064268.1 hypothetical protein -
GWK63_RS16275 3508599..3510020 + 1422 WP_166498174.1 hypothetical protein -
GWK63_RS16280 3510294..3510539 + 246 WP_202795779.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GWK63_RS16285 3510526..3510825 + 300 WP_039998565.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GWK63_RS16290 3510852..3511124 - 273 WP_007397369.1 DUF2274 domain-containing protein -
GWK63_RS16295 3511121..3512329 - 1209 WP_007397368.1 TrbI/VirB10 family protein -
GWK63_RS16300 3512326..3513327 - 1002 WP_039998564.1 P-type conjugative transfer protein TrbG -
GWK63_RS16305 3513324..3513605 - 282 Protein_3201 conjugal transfer protein TrbF -
GWK63_RS16310 3513823..3513978 - 156 Protein_3202 DUF736 family protein -
GWK63_RS16315 3513977..3515416 - 1440 Protein_3203 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3451207..3524512 73305


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-92)

Antitoxin

Antitoxin ParD

(1-67)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11703.42 Da        Isoelectric Point: 6.8441

>T152290 WP_039998565.1 NZ_CP050139:3510526-3510825 [Komagataeibacter rhaeticus]
MPTCRKTRLAEDDIVNIYMQGVRDFGPRQAEIYHAGLSDAFDLIASHPQLAPERHEFDPPIRLHRHRAHHILYLIDDDGV
LIVRVLPRLRRWERLMETD

Download         Length: 300 bp

>T152290 NZ_CP066094:c4104145-4103735 [Enterobacter hormaechei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGGCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGGACGCCGTGGATGCTTAATACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8883.87 Da        Isoelectric Point: 6.4618

>AT152290 WP_202795779.1 NZ_CP050139:3510294-3510539 [Komagataeibacter rhaeticus]
MNVSLPDPMKEWVEAQAKTGRYSNASDYVRDLIRRDQEARAAHDEVQAHITAGLRSGVGTRSMKQLLQDARAAAGTTDAD
L

Download         Length: 246 bp

>AT152290 NZ_CP066094:c4104392-4104126 [Enterobacter hormaechei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References