Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 172249..172520 Replicon chromosome
Accession NZ_CP049936
Organism Escherichia coli strain JL05

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 172379..172482 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 172249..172520 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9V97_RS00805 168804..169466 - 663 WP_000944256.1 exodeoxyribonuclease X -
G9V97_RS00810 169490..170146 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
G9V97_RS00815 170248..170478 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G9V97_RS00820 170617..170991 + 375 WP_000204699.1 CopC domain-containing protein YobA -
G9V97_RS00825 170995..171867 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
G9V97_RS00830 171880..172221 + 342 WP_000976472.1 YebY family protein -
- 172249..172520 - 272 - - Antitoxin
- 172379..172482 + 104 - - Toxin
G9V97_RS00835 172617..173273 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
G9V97_RS00840 173274..173465 - 192 WP_001296140.1 YebW family protein -
G9V97_RS00845 173570..173806 - 237 WP_001295499.1 DUF1480 family protein -
G9V97_RS00850 173924..175363 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 150235..175369 25134


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T151780 NZ_CP049936:172379-172482 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT151780 NZ_CP049936:c172520-172249 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References