Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2691773..2692223 Replicon chromosome
Accession NZ_CP049737
Organism Pseudomonas sp. AN-B15

Toxin (Protein)


Gene name relE Uniprot ID A0A2A2PFH8
Locus tag GTQ41_RS12125 Protein ID WP_045122487.1
Coordinates 2691773..2692042 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A031G898
Locus tag GTQ41_RS12130 Protein ID WP_003225628.1
Coordinates 2692032..2692223 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTQ41_RS12125 (GTQ41_12145) 2691773..2692042 - 270 WP_045122487.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GTQ41_RS12130 (GTQ41_12150) 2692032..2692223 - 192 WP_003225628.1 hypothetical protein Antitoxin
GTQ41_RS12135 (GTQ41_12155) 2692497..2693444 - 948 WP_047293969.1 transporter -
GTQ41_RS12140 (GTQ41_12160) 2693655..2694695 + 1041 WP_047293971.1 AraC family transcriptional regulator -
GTQ41_RS12145 (GTQ41_12165) 2694837..2695724 + 888 WP_047293972.1 Dyp-type peroxidase -
GTQ41_RS12150 (GTQ41_12170) 2695752..2696717 + 966 WP_047293973.1 Gfo/Idh/MocA family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10185.68 Da        Isoelectric Point: 9.7677

>T151478 WP_045122487.1 NZ_CP049737:c2692042-2691773 [Pseudomonas sp. AN-B15]
VRVDWRPEARTQLWQTLNYIADRNAVAASQLNAAIEAATSALPLHPYLYRFGKVAGTREIVVHPNYVVVYRVTDRIEILN
LLHARQAYP

Download         Length: 270 bp

>T151478 NZ_CP065534:c3152481-3152065 [Lonsdalea populi]
GTGGCCCAGTGGCAATGTGATCTCAAAGTTTCCTGGCGCATGCAGCTGTTCTCTCTGCTGGTGCACGGGATTATGGTGCT
CTTGATTCTGCTGGCCCCGTGGCCGAGCGGTTATGCGCCGCTATGGCTGGGGCTGGTGTCTCTGGTGATGTTCGGATTCA
TCCGCAGCCAGCGCAACATCAAATCCCGCCACGGCGCGATCTCGCTGCACGGCGAACGCCGTCTGCGCTGGCAGCAGCGA
GAGTGGCGTATCGTCAAACGTCCGTGGATGCTTAAAAGCGGTATTCTGCTGTCGCTGCGCGCAGCGGACGGCGCGGCCCA
GGAACAGCGTCTGTGGCTCTCTTCAGACAGCATGGGGCGGGATGAGTGGCGGCACCTGCGGCAGCTTTTGCTGCAAAAGG
ACAGCTGCGCAGGGTAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7108.96 Da        Isoelectric Point: 4.4184

>AT151478 WP_003225628.1 NZ_CP049737:c2692223-2692032 [Pseudomonas sp. AN-B15]
MSAELSLIVSDFETPEQAASYDRWFRAQVQASMDDPRPNIPHEQVMAEMRALIESKLNKNSAG

Download         Length: 192 bp

>AT151478 NZ_CP065534:c3152728-3152462 [Lonsdalea populi]
ATGGATATCAATGATAAATCACGCATTCACTGGGCCTGCCGGCGCGGCATGCGTGAGCTGGATATTTCCATCATGCCGTT
TTTCGAGCATGACTACGATACGTTAAACGATAGCGACAAAAATGCTTTTGTCCGCCTGTTGCAGTGCGACGATCCCGATC
TGTTCAACTGGTTGATGAACCACGGCGAACCATCAGATCAGGAGCTCAAACGCATGGTTTCCCTTATTCAGACGCGAAAT
AAACACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A2PFH8

Antitoxin

Source ID Structure
AlphaFold DB A0A031G898

References