Detailed information of TA system TA151123

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 2875717..2875937
• Replicon: chromosome
• Accession: NZ_CP049278
• Organism: Shigella boydii strain 600690

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: -
• Locus tag: G5S56_RS14215
• Protein ID: WP_078166279.1
• Coordinates: 2875830..2875937 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	2875717..2875783 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G5S56_RS14190	2870995..2872389	-	1395	WP_024258159.1	inverse autotransporter invasin YchO	-
G5S56_RS14195	2872575..2872928	+	354	WP_001169669.1	DsrE/F sulfur relay family protein YchN	-
G5S56_RS14200	2872972..2873667	-	696	WP_078166256.1	glutathione-specific gamma-glutamylcyclotransferase	-
G5S56_RS14205	2873825..2874055	-	231	WP_001146444.1	putative cation transport regulator ChaB	-
G5S56_RS14210	2874325..2875425	+	1101	WP_001295620.1	sodium-potassium/proton antiporter ChaA	-
-	2875717..2875783	-	67	-	-	Antitoxin
G5S56_RS14215	2875830..2875937	+	108	WP_078166279.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
G5S56_RS14220	2876086..2876940	-	855	WP_000811073.1	3-deoxy-8-phosphooctulonate synthase	-
G5S56_RS14225	2876976..2877785	-	810	WP_078166257.1	invasion regulator SirB1	-
G5S56_RS14230	2877789..2878181	-	393	WP_000200382.1	invasion regulator SirB2	-
G5S56_RS14235	2878178..2879011	-	834	WP_000386244.1	peptide chain release factor N(5)-glutamine methyltransferase	-
G5S56_RS14240	2879011..2880093	-	1083	WP_000804726.1	peptide chain release factor 1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.84 Da
• Isoelectric Point: 12.5163

>T151123 WP_078166279.1 NZ_CP049278:2875830-2875937 [Shigella boydii]
MTLAQFAMIFWHNLAAPILAGIITAAIVSWWRNRK

Nucleotide

• Length: 108 bp

>T151123 NZ_CP065341:c2656817-2655495 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCTGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTTACCGCCTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCGGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCACTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin

Nucleotide

• Length: 67 bp

>AT151123 NZ_CP049278:c2875783-2875717 [Shigella boydii]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCT

Structures

Antitoxin