Detailed information of TA system TA151085

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 3311260..3311783
• Replicon: chromosome
• Accession: NZ_CP049250
• Organism: Rhizobium rhizoryzae strain DSM 29514

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: G6N80_RS21880
• Protein ID: WP_165136804.1
• Coordinates: 3311260..3311532 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: A0A0Q7Z0L2
• Locus tag: G6N80_RS21885
• Protein ID: WP_062552917.1
• Coordinates: 3311529..3311783 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G6N80_RS21855	3306804..3307691	-	888	WP_062552912.1	branched-chain amino acid aminotransferase	-
G6N80_RS21860	3307875..3308036	-	162	WP_156379017.1	hypothetical protein	-
G6N80_RS21865	3308127..3309032	-	906	WP_062552913.1	LysR family transcriptional regulator	-
G6N80_RS21870	3309140..3310321	+	1182	WP_165136801.1	MFS transporter	-
G6N80_RS21875	3310414..3311241	+	828	WP_165137259.1	aldo/keto reductase	-
G6N80_RS21880	3311260..3311532	-	273	WP_165136804.1	Txe/YoeB family addiction module toxin	Toxin
G6N80_RS21885	3311529..3311783	-	255	WP_062552917.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
G6N80_RS21890	3311833..3312420	-	588	WP_062552918.1	DedA family protein	-
G6N80_RS21895	3312552..3312929	+	378	WP_165136807.1	MbcA/ParS/Xre antitoxin family protein	-
G6N80_RS21900	3312889..3313650	+	762	WP_165136810.1	RES family NAD+ phosphorylase	-
G6N80_RS21905	3313643..3314089	-	447	WP_165136813.1	MarR family transcriptional regulator	-
G6N80_RS21910	3314149..3314877	+	729	WP_062553231.1	thioredoxin family protein	-
G6N80_RS21915	3314900..3315370	+	471	WP_062552922.1	DUF1579 domain-containing protein	-
G6N80_RS21920	3315400..3316197	+	798	WP_062552923.1	VOC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-71)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10550.13 Da
• Isoelectric Point: 9.5031

>T151085 WP_165136804.1 NZ_CP049250:c3311532-3311260 [Rhizobium rhizoryzae]
MKLVWTEQAWADYEFWVESDQAVVLRIHQLIKDMKRSPFSGIGKPEPLKGSLSGFWSRRITADHRIVYNVAGAGEDQRLQ
IIQCRYHYVK

Nucleotide

• Length: 273 bp

>T151085 NZ_CP065228:3742579-3743502 [Xanthomonas oryzae pv. oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACTGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9395.52 Da
• Isoelectric Point: 4.6338

>AT151085 WP_062552917.1 NZ_CP049250:c3311783-3311529 [Rhizobium rhizoryzae]
MPHVRFTEFRQNFASHFDAVLESRAPLLVTRQGAESVVVIAEGEFESMQETLHLLSNPANADRLRESMEQLAGGKVIERD
PTGE

Nucleotide

• Length: 255 bp

>AT151085 NZ_CP065228:3741983-3742582 [Xanthomonas oryzae pv. oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGTACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTCGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Structures

Antitoxin

• AlphaFold DB: A0A0Q7Z0L2