Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014633..2014904 Replicon chromosome
Accession NZ_CP049204
Organism Escherichia coli strain PapM-32-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014763..2014866 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014633..2014904 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6Z93_RS09490 2011188..2011850 - 663 WP_000944256.1 exodeoxyribonuclease X -
G6Z93_RS09495 2011874..2012530 - 657 WP_044191542.1 carbon-nitrogen hydrolase family protein -
G6Z93_RS09500 2012632..2012862 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G6Z93_RS09505 2013001..2013375 + 375 WP_000168738.1 CopC domain-containing protein YobA -
G6Z93_RS09510 2013379..2014251 + 873 WP_044191540.1 copper homeostasis membrane protein CopD -
G6Z93_RS09515 2014264..2014605 + 342 WP_000976472.1 YebY family protein -
- 2014633..2014904 - 272 - - Antitoxin
- 2014763..2014866 + 104 - - Toxin
G6Z93_RS09520 2015001..2015657 + 657 WP_001718411.1 protein-serine/threonine phosphatase -
G6Z93_RS09525 2015658..2015849 - 192 WP_001313035.1 YebW family protein -
G6Z93_RS09530 2015954..2016190 - 237 WP_001295499.1 DUF1480 family protein -
G6Z93_RS09535 2016308..2017747 - 1440 WP_001718410.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T151024 NZ_CP049204:2014763-2014866 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT151024 NZ_CP049204:c2014904-2014633 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References