Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 386762..386996 | Replicon | chromosome |
| Accession | NZ_CP049185 | ||
| Organism | Shigella sonnei strain 19.0821.3486 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 386892..386995 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 386762..386996 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G6O60_RS02050 | 383317..383979 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| G6O60_RS02055 | 384003..384659 | - | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| G6O60_RS02060 | 384761..384991 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| G6O60_RS02065 | 385130..385504 | + | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| G6O60_RS02070 | 385508..386380 | + | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| G6O60_RS02075 | 386393..386734 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 386762..386996 | - | 235 | - | - | Antitoxin |
| - | 386892..386995 | + | 104 | - | - | Toxin |
| G6O60_RS02080 | 387117..388193 | - | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| G6O60_RS02085 | 388230..388475 | - | 246 | Protein_408 | IS1 family transposase | - |
| G6O60_RS02095 | 389809..390263 | - | 455 | Protein_410 | IS1-like element IS1A family transposase | - |
| G6O60_RS02100 | 390292..390552 | - | 261 | WP_077447296.1 | excisionase | - |
| G6O60_RS02105 | 390697..391853 | + | 1157 | WP_254000227.1 | IS3-like element IS600 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 / ipaH9.8 | 323379..413944 | 90565 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T150835 NZ_CP049185:386892-386995 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT150835 NZ_CP049185:c386996-386762 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
