Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 236443..236677 | Replicon | chromosome |
| Accession | NZ_CP049175 | ||
| Organism | Shigella sonnei strain 7111.69 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 236444..236547 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 236443..236677 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G6O62_RS01250 | 232877..233137 | + | 261 | WP_077447296.1 | excisionase | - |
| G6O62_RS01255 | 233166..233620 | + | 455 | Protein_247 | IS1-like element IS1A family transposase | - |
| G6O62_RS01260 | 233715..234943 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| G6O62_RS01265 | 234954..235199 | + | 246 | Protein_249 | IS1 family transposase | - |
| G6O62_RS01270 | 235236..236312 | + | 1077 | WP_052987259.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 236443..236677 | + | 235 | - | - | Antitoxin |
| - | 236444..236547 | - | 104 | - | - | Toxin |
| G6O62_RS01275 | 236705..237046 | - | 342 | WP_000976476.1 | YebY family protein | - |
| G6O62_RS01280 | 237059..237931 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| G6O62_RS01285 | 237935..238309 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| G6O62_RS01290 | 238448..238678 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| G6O62_RS01295 | 238780..239436 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| G6O62_RS01300 | 239460..240122 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 / ipaH9.8 | 222092..242179 | 20087 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T150768 NZ_CP049175:c236547-236444 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT150768 NZ_CP049175:236443-236677 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
