Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3813013..3813247 Replicon chromosome
Accession NZ_CP049171
Organism Shigella sonnei strain 0401930105

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3813143..3813246 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3813013..3813247 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6O59_RS18985 3809568..3810230 - 663 WP_000944256.1 exodeoxyribonuclease X -
G6O59_RS18990 3810254..3810910 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
G6O59_RS18995 3811012..3811242 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G6O59_RS19000 3811381..3811755 + 375 WP_000168735.1 CopC domain-containing protein YobA -
G6O59_RS19005 3811759..3812631 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
G6O59_RS19010 3812644..3812985 + 342 WP_000976476.1 YebY family protein -
- 3813013..3813247 - 235 - - Antitoxin
- 3813143..3813246 + 104 - - Toxin
G6O59_RS19015 3813368..3814444 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
G6O59_RS19020 3814481..3814726 - 246 Protein_3693 IS1 family transposase -
G6O59_RS19030 3816060..3816514 - 455 Protein_3695 IS1-like element IS1A family transposase -
G6O59_RS19035 3816543..3816803 - 261 WP_077447296.1 excisionase -
G6O59_RS19040 3816948..3818104 + 1157 WP_087879964.1 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 / ipaH9.8 3807511..3840199 32688


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150734 NZ_CP049171:3813143-3813246 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT150734 NZ_CP049171:c3813247-3813013 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References