Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2170841..2171109 Replicon chromosome
Accession NZ_CP048647
Organism Escherichia coli strain GW-AmxH19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2170969..2171071 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2170841..2171109 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3273_RS10090 2167395..2168057 - 663 WP_000944256.1 exodeoxyribonuclease X -
G3273_RS10095 2168080..2168736 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
G3273_RS10100 2168838..2169068 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G3273_RS10105 2169207..2169581 + 375 WP_000168747.1 CopC domain-containing protein YobA -
G3273_RS10110 2169585..2170457 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
G3273_RS10115 2170470..2170811 + 342 WP_000977376.1 YebY family protein -
- 2170841..2171109 - 269 - - Antitoxin
- 2170969..2171071 + 103 - - Toxin
G3273_RS10120 2171206..2171862 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
G3273_RS10125 2171863..2172054 - 192 WP_001296140.1 YebW family protein -
G3273_RS10130 2172159..2172395 - 237 WP_001295499.1 DUF1480 family protein -
G3273_RS10135 2172513..2173952 - 1440 WP_001467894.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T149819 NZ_CP048647:2170969-2171071 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT149819 NZ_CP048647:c2171109-2170841 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References