Detailed information of TA system TA149776

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 604746..605668
• Replicon: chromosome
• Accession: NZ_CP048629
• Organism: Pseudomonas sp. OIL-1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: G3M63_RS02760
• Protein ID: WP_150302402.1
• Coordinates: 604746..605204 (-)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: G3M63_RS02765
• Protein ID: WP_150302399.1
• Coordinates: 605216..605668 (-)
• Length: 151 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G3M63_RS02725	599889..600149	-	261	WP_150302190.1	hypothetical protein	-
G3M63_RS02730	600960..601922	-	963	WP_163981811.1	tyrosine-type recombinase/integrase	-
G3M63_RS02735	601919..602296	-	378	WP_150302191.1	DUF2513 domain-containing protein	-
G3M63_RS02740	602453..603067	+	615	WP_150302192.1	hypothetical protein	-
G3M63_RS02745	603265..603636	-	372	WP_163981812.1	hypothetical protein	-
G3M63_RS02750	603851..604135	+	285	WP_150302401.1	hypothetical protein	-
G3M63_RS02755	604170..604505	+	336	WP_150302400.1	hypothetical protein	-
G3M63_RS02760	604746..605204	-	459	WP_150302402.1	RES domain-containing protein	Toxin
G3M63_RS02765	605216..605668	-	453	WP_150302399.1	DUF2384 domain-containing protein	Antitoxin
G3M63_RS02770	606359..606547	-	189	WP_150302398.1	type II toxin-antitoxin system VapB family antitoxin	-
G3M63_RS02775	607842..608297	+	456	WP_150302397.1	hypothetical protein	-
G3M63_RS02780	608746..609363	+	618	WP_163981813.1	hypothetical protein	-
G3M63_RS02785	609384..610181	-	798	WP_150302439.1	IS21-like element helper ATPase IstB	-
G3M63_RS02790	610178..610525	-	348	WP_163981814.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	577532..622128	44596

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-148)

Antitoxin

• Antitoxin Xre (20-150)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 16614.98 Da
• Isoelectric Point: 6.8716

>T149776 WP_150302402.1 NZ_CP048629:c605204-604746 [Pseudomonas sp. OIL-1]
IEYFRIVKKKWASTAFDGEGARRHGGRWNSKGQRCVYLSSSISLATLEVLVHLQSSDLLAAYVLFSVKIPVEHVRSLAKS
DLPSNWQADPAPSETAAIGDGWLVSGDGVALVVPSTVIVQEKNILLNPAHPAFELIVATSTEVNFEFDPRLK

Nucleotide

• Length: 459 bp

>T149776 NZ_CP064241:c4717611-4717078 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 151 a.a.
• Molecular weight: 16545.13 Da
• Isoelectric Point: 9.4245

>AT149776 WP_150302399.1 NZ_CP048629:c605668-605216 [Pseudomonas sp. OIL-1]
METVHIKTYKPQRSKTESLWEKIGLPSRGEKLHSAVREGVSYVVYERLADAGGLDIKRLSKVLLISGTTIHRRTKSGRFN
TLESDKIVMFAEVLEAAVNLFEGDKEAARQWMNAPVKGLGGKAPMDMLGTNVEAEAVLDLIGRLEHGVIA

Nucleotide

• Length: 453 bp

>AT149776 NZ_CP064241:c4717888-4717622 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA