147068

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1585657..1586342 Replicon chromosome
Accession NZ_CP047652
Organism Bombella sp. KACC 21507

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GT348_RS07150 Protein ID WP_160619112.1
Coordinates 1585657..1586064 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GT348_RS07155 Protein ID WP_160619113.1
Coordinates 1586061..1586342 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT348_RS07100 1580959..1581195 + 237 WP_160619103.1 hypothetical protein -
GT348_RS07105 1581192..1581428 + 237 WP_160619104.1 hypothetical protein -
GT348_RS07110 1581425..1581799 + 375 WP_160619105.1 hypothetical protein -
GT348_RS07115 1581796..1582050 + 255 WP_160619106.1 hypothetical protein -
GT348_RS07120 1582032..1583354 + 1323 WP_160619107.1 hypothetical protein -
GT348_RS07125 1583369..1583674 + 306 WP_160619108.1 hypothetical protein -
GT348_RS07130 1583671..1583886 + 216 WP_160619109.1 hypothetical protein -
GT348_RS07135 1583873..1584115 + 243 WP_160619110.1 hypothetical protein -
GT348_RS07140 1584117..1584758 + 642 WP_160619111.1 DUF935 family protein -
GT348_RS07145 1584719..1585444 + 726 WP_160619489.1 DUF935 family protein -
GT348_RS07150 1585657..1586064 - 408 WP_160619112.1 type II toxin-antitoxin system VapC family toxin Toxin
GT348_RS07155 1586061..1586342 - 282 WP_160619113.1 antitoxin Antitoxin
GT348_RS07160 1586389..1586640 - 252 WP_160619114.1 hypothetical protein -
GT348_RS07165 1587276..1587836 - 561 WP_160619115.1 hypothetical protein -
GT348_RS07170 1587928..1588437 - 510 WP_160619116.1 hypothetical protein -
GT348_RS07175 1588529..1589026 - 498 WP_160619117.1 hypothetical protein -
GT348_RS07180 1589116..1589619 - 504 WP_160619118.1 hypothetical protein -
GT348_RS07185 1589719..1590267 - 549 WP_160619119.1 hypothetical protein -
GT348_RS07190 1590484..1591038 - 555 WP_160619120.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1567008..1608194 41186


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-117)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14496.74 Da        Isoelectric Point: 5.8854

>T147068 WP_160619112.1 NZ_CP047652:c1586064-1585657 [Bombella sp. KACC 21507]
MKQLYMLDTNIVSELAQNPHGPVSHKIAEIGDDAICVSIITAAELHYGCAKKGSAKLTHQIEAILNSVKIMALDIPVDNQ
YGTIRTQLEASGHVISPHNLLVATQASALGAIVVTSNIEEFGKLEGLKLENWLAL

Download         Length: 408 bp

>T147068 NZ_CP062855:c4321205-4320840 [Escherichia coli O20:H12]
ATTACCCATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTCCCGACTACT
GGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTGAAGCTGGCA
TTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTCAGCACTTGT
CCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGACAATTACAG
AACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10286.85 Da        Isoelectric Point: 5.0634

>AT147068 WP_160619113.1 NZ_CP047652:c1586342-1586061 [Bombella sp. KACC 21507]
MEGCVPYSSLIKTSTPREARLFRNNKSQAVRIPVDFELPGKSVLIHKDGDCLIIEPLAHKGLSAALANLQPLLPEDYFPE
INTTSQPLSEIEL

Download         Length: 282 bp

>AT147068 NZ_CP062855:c4321671-4321303 [Escherichia coli O20:H12]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGTCTGACCTGCAAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References