Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3625570..3625715 Replicon chromosome
Accession NZ_CP047648
Organism Klebsiella pneumoniae strain 156070

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3625577..3625679 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3625570..3625715 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTK58_RS17890 3621102..3622535 + 1434 WP_160192556.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GTK58_RS17895 3622651..3622890 + 240 WP_002911393.1 YebV family protein -
GTK58_RS17900 3622988..3623179 + 192 WP_002911395.1 YebW family protein -
GTK58_RS17905 3623176..3623829 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
GTK58_RS17910 3623986..3624954 + 969 WP_004151446.1 VirK/YbjX family protein -
GTK58_RS17915 3625059..3625202 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3625570..3625715 + 146 - - Antitoxin
- 3625577..3625679 - 103 - - Toxin
GTK58_RS17920 3625838..3626176 - 339 WP_002911404.1 YebY family protein -
GTK58_RS17925 3626193..3627062 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
GTK58_RS17930 3627066..3627440 - 375 WP_004151448.1 CopC domain-containing protein YobA -
GTK58_RS17935 3627553..3627783 + 231 WP_002911406.1 DNA polymerase III subunit theta -
GTK58_RS17940 3627862..3628521 + 660 WP_002911407.1 exodeoxyribonuclease X -
GTK58_RS17945 3628525..3630585 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T147033 NZ_CP047648:c3625679-3625577 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT147033 NZ_CP047648:3625570-3625715 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References