Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 956333..956601 Replicon chromosome
Accession NZ_CP047600
Organism Escherichia coli O84:H7 strain Trh52

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 956371..956473 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 956333..956601 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GUK18_RS04755 953490..954929 + 1440 WP_203164434.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GUK18_RS04760 955047..955283 + 237 WP_001295499.1 DUF1480 family protein -
GUK18_RS04765 955388..955579 + 192 WP_001317886.1 YebW family protein -
GUK18_RS04770 955580..956236 - 657 WP_001357783.1 protein-serine/threonine phosphatase -
- 956333..956601 + 269 - - Antitoxin
- 956371..956473 - 103 - - Toxin
GUK18_RS04775 956631..956972 - 342 WP_024223804.1 YebY family protein -
GUK18_RS04780 956985..957857 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
GUK18_RS04785 957861..958235 - 375 WP_000168747.1 CopC domain-containing protein YobA -
GUK18_RS04790 958374..958604 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GUK18_RS04795 958706..959362 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
GUK18_RS04800 959385..960047 + 663 WP_203164435.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T146867 NZ_CP047600:c956473-956371 [Escherichia coli O84:H7]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT146867 NZ_CP047600:956333-956601 [Escherichia coli O84:H7]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCGGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References