Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3823275..3823546 Replicon chromosome
Accession NZ_CP047127
Organism Escherichia coli K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3823405..3823508 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3823275..3823546 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GRF62_RS18210 3819830..3820492 - 663 WP_000944256.1 exodeoxyribonuclease X -
GRF62_RS18215 3820516..3821172 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GRF62_RS18220 3821274..3821504 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GRF62_RS18225 3821643..3822017 + 375 WP_000168747.1 CopC domain-containing protein YobA -
GRF62_RS18230 3822021..3822893 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
GRF62_RS18235 3822906..3823247 + 342 WP_000976476.1 YebY family protein -
- 3823275..3823546 - 272 - - Antitoxin
- 3823405..3823508 + 104 - - Toxin
GRF62_RS18240 3823643..3824299 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GRF62_RS18245 3824300..3824491 - 192 WP_000457842.1 YebW family protein -
GRF62_RS18250 3824596..3824832 - 237 WP_001295499.1 DUF1480 family protein -
GRF62_RS18255 3824950..3826389 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T145459 NZ_CP047127:3823405-3823508 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT145459 NZ_CP047127:c3823546-3823275 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References