Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 2053435..2053657 Replicon chromosome
Accession NZ_CP047127
Organism Escherichia coli K-12

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag GRF62_RS09785 Protein ID WP_000141634.1
Coordinates 2053550..2053657 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 2053435..2053501 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GRF62_RS09765 2048876..2049778 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
GRF62_RS09770 2049789..2050772 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
GRF62_RS09775 2050769..2051773 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
GRF62_RS09780 2051803..2053074 - 1272 WP_001295225.1 transporter -
- 2053435..2053501 - 67 - - Antitoxin
GRF62_RS09785 2053550..2053657 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
GRF62_RS09790 2053744..2055423 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
GRF62_RS09795 2055420..2055611 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
GRF62_RS09800 2055608..2057179 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
GRF62_RS09805 2057452..2057640 + 189 WP_001063318.1 YhjR family protein -
GRF62_RS09810 2057652..2058404 + 753 Protein_1898 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T145448 WP_000141634.1 NZ_CP047127:2053550-2053657 [Escherichia coli K-12]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T145448 NZ_CP062386:c183502-183407 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 67 bp

>AT145448 NZ_CP047127:c2053501-2053435 [Escherichia coli K-12]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References