Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1019536..1019807 Replicon chromosome
Accession NZ_CP047002
Organism Escherichia coli strain J-8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1019574..1019677 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1019536..1019807 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQF94_RS05000 1016693..1018132 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GQF94_RS05005 1018250..1018486 + 237 WP_001295499.1 YebV family protein -
GQF94_RS05010 1018591..1018782 + 192 WP_001296140.1 YebW family protein -
GQF94_RS05015 1018783..1019439 - 657 WP_000812735.1 protein-serine/threonine phosphatase -
- 1019536..1019807 + 272 - - Antitoxin
- 1019574..1019677 - 104 - - Toxin
GQF94_RS05020 1019835..1020176 - 342 WP_000976472.1 YebY family protein -
GQF94_RS05025 1020189..1021061 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
GQF94_RS05030 1021065..1021439 - 375 WP_000204699.1 CopC domain-containing protein YobA -
GQF94_RS05035 1021578..1021808 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GQF94_RS05040 1021910..1022566 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
GQF94_RS05045 1022590..1023252 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T145256 NZ_CP047002:c1019677-1019574 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT145256 NZ_CP047002:1019536-1019807 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References