Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 552979..553562 Replicon chromosome
Accession NZ_CP046914
Organism Paraburkholderia acidisoli strain DHF22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FAZ98_RS16760 Protein ID WP_158952434.1
Coordinates 553182..553562 (+) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FAZ98_RS16755 Protein ID WP_158952433.1
Coordinates 552979..553185 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ98_RS16740 548307..551609 + 3303 WP_158952430.1 DUF802 domain-containing protein -
FAZ98_RS16745 551606..552256 + 651 WP_158952431.1 OmpA family protein -
FAZ98_RS16750 552249..552911 + 663 WP_158952432.1 DUF2894 domain-containing protein -
FAZ98_RS16755 552979..553185 + 207 WP_158952433.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FAZ98_RS16760 553182..553562 + 381 WP_158952434.1 VapC toxin family PIN domain ribonuclease Toxin
FAZ98_RS16765 553563..554720 - 1158 WP_199272381.1 3-deoxy-7-phosphoheptulonate synthase -
FAZ98_RS16770 554944..555951 - 1008 WP_158952435.1 sterol desaturase family protein -
FAZ98_RS16775 555962..556987 - 1026 WP_158952436.1 YncE family protein -
FAZ98_RS16780 557212..558561 + 1350 WP_158952437.1 Nramp family divalent metal transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13886.98 Da        Isoelectric Point: 6.2069

>T145154 WP_158952434.1 NZ_CP046914:553182-553562 [Paraburkholderia acidisoli]
MSVLIDTSVWVDHFRHGNPELVALITRDEALTHPFVILELACGTPPAPRAQTLRDIGLLQHAQQATWAEVMQFIELEQLY
GKGCGSVDLTLLASTLVTPGARLWSLDRRLAALADRLNVAWHSAAH

Download         Length: 381 bp

>T145154 NZ_CP062322:2317329-2317595 [Staphylococcus aureus]
ATGAGCAATTATACGGTTAAGATTAAAAATTCGGCGAAATCAGATTTAAAGAAAATAAAACATTCTTATTTAAAAAAGCC
ATTTTTAGAAATTGTTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCCTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACTGTAGATGATCGAAATAAAGAAGTATTAATA
TTATCGGCGTGGTCACATTATGATTAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7384.46 Da        Isoelectric Point: 6.1868

>AT145154 WP_158952433.1 NZ_CP046914:552979-553185 [Paraburkholderia acidisoli]
MRTTVTIDDALYQQALELAGPGIDKADLFRVAIQTFVRVQAAKRLAALGGSAPQMADIPRQRPDYDAP

Download         Length: 207 bp

>AT145154 NZ_CP062322:2317072-2317329 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGATGATTGGAAAAGTATACAAGAAACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTAAGAGATAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References