Detailed information of TA system TA143793

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YefM(antitoxin)
• Location: 155500..156068
• Replicon: chromosome
• Accession: NZ_CP046269
• Organism: Vibrio spartinae strain 3.6

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: Vspart_RS17360
• Protein ID: WP_182288961.1
• Coordinates: 155778..156068 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7D7X6I1
• Locus tag: Vspart_RS17355
• Protein ID: WP_038179832.1
• Coordinates: 155500..155781 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Vspart_RS17340	151823..153427	+	1605	WP_182288958.1	S-type pyocin domain-containing protein	-
Vspart_RS17345	153424..153681	+	258	WP_182288959.1	bacteriocin immunity protein	-
Vspart_RS17350	153976..154854	+	879	WP_182288960.1	HEPN domain-containing protein	-
Vspart_RS17355	155500..155781	+	282	WP_038179832.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
Vspart_RS17360	155778..156068	+	291	WP_182288961.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Vspart_RS17365	156062..156322	+	261	WP_182288962.1	hypothetical protein	-
Vspart_RS17370	158059..160905	+	2847	WP_182288963.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-76)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10971.69 Da
• Isoelectric Point: 4.3313

>T143793 WP_182288961.1 NZ_CP046269:155778-156068 [Vibrio spartinae]
MNVVWSPLALEKLGDAAEFISLDDPLAAENWVNDVFDKTELLGIMPEMGRVVPELPSTNYREIIFGHYRIIYSCSVEIRI
LTVRNCRQILTKDDVC

Nucleotide

• Length: 291 bp

>T143793 NZ_CP061368:c195375-194869 [Wenzhouxiangella sp. AB-CW3]
ATCCAGGCATCCAGGCACGACCGGGCGATTCCCTGTGGGCCGGGCGGGTCGATGCACGATTATGTGCCGTTCTACTTTGG
CCCCTTGTCACCGATGATGCTGAACCTCAAGACCGGCCGGGTTGCCGGTTACCAGGAAGGTCAGGAGCCGCTGATCTATC
TGGTGTCGACCGCTCAGAAGGTTCAGGAAACCGGCGCCGAATTCGTCTTCTCCGATGGCCACGGGCTGGCGGCATTCACC
GAGTGGTTTGATGATCTTGATTTCCTGGAACAAATTGATTGGCAGGTCGTGAAGGCACGCTATTGGGCGGATACCGCAAA
TGATATGGATCGACAGCGCAAAAAGCAGGCGGAGTTCCTGGTGCATCGCTTCTGCCCCTGGGCGCTTATTGGGGAAATTG
TGGTCCTGAACCAACGCATGAAAGAGCGCGTCGAGGCGGTATTGGCTGGATACCCGGCGGCTTCGGGCGTGGCTGTTTCC
GAGCGCCCGGACTGGTACTATCATTAG

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10591.23 Da
• Isoelectric Point: 6.3999

>AT143793 WP_038179832.1 NZ_CP046269:155500-155781 [Vibrio spartinae]
MKRIRFDQDIKPLSEFRSGVASFIKQINETRRPLVITQRGKGVAVVLDVEEYEAMQEKIELLEEMRAAEAQLASGMGISN
EDARANVLERIKK

Nucleotide

• Length: 282 bp

>AT143793 NZ_CP061368:c194852-193761 [Wenzhouxiangella sp. AB-CW3]
ATGATTGAGCATACACAAGGCAACCTGCTCAGCGCTGACGCGGAAGCGCTGGTCAACACGGTGAATTGCGTTGGCTACAT
GGGCAAAGGAATTGCCCTGCAGTTCAAGCAGGCGTTTCCGGAGAATTTCAAGGCGTATCAGCGGGCGTGCAAGGCGGAAG
AGGTGCGGCCCGGAAGGATGTTCGTATTCGAGACCGGGAACCTGGTCAATCCCCGCTATATCATCAACTTTCCGACCAAG
AATCACTGGCGGGGCAAGTCCCGCATGCAGGATATCGAGCAAGGCTTGCAGGACCTCATCGCTGTTATCCGGAGGCTAAA
CATTCGCTCGGTTGCGATCCCGCCGCTTGGCAGCGGACTGGGGGGATTGAATTGGCTGGAAGTAAAGCCGCGAATCGAGG
CGGCGTTTGCCGATCTTGCGGACGTTCATGTATTGCTCTATGAACCCAAGGGTGCGCCCGAAGCAGCCCGCATGCTGGTC
AGGACCAAGCGCCCGCATTGGACGGTGGCGCGTGCCCTTTTCATCAGCCTGATGGATCGCTATGGGGAGCTGGATTACCG
CCGGACGCTACTGGAGATACAGAAGCTTGCCTACTTCCTGCAGGAGGCCGGGGAAGGACTAAGGCTACGTTACGAAAAAG
GGCTTTATGGCCCTTACGCGCACAACCTGAACAAAGTGCTGGAGACCCTGGAAGGGCATTACACGCGCGGATTTGGTGAC
AGTCAGAAGCCCGATACTGAAATTGAATTGATGGACGGCGCGGTCGACGAGGCTGAACGGTTTCTGGCTGAATACCAGGA
GTCCCGGGAGCGCCTGGACCAGGTCACAGAACTCATCGCAGGCTTCGAAACGCCATACGGAATGGAGCTGCTGTCCAGCG
TGCATTGGGTTGCAGCGCATGATGAGCGGCTGGTCAGTAATGCGGATGAGGCCGTGGAAGCGGTTCATGCCTGGAATGAC
CGAAAGCGGAGCATGTTCCAGCCGAAGCACATCAGGGTCGCATGGCGGCATTTGGAGGATCACGGTTGGCTGGGTCTCGA
TCAGGCTGCCTCGCGCGGGCCGGGTTCAGGGAACGCTGGAAGGCCGAGGTAA

Structures

Antitoxin

• AlphaFold DB: A0A7D7X6I1