Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1874713..1874947 | Replicon | chromosome |
| Accession | NZ_CP045932 | ||
| Organism | Shigella sonnei strain AUSMDU00010534 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1874843..1874946 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1874713..1874947 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GJE15_RS09435 | 1871268..1871930 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| GJE15_RS09440 | 1871954..1872610 | - | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| GJE15_RS09445 | 1872712..1872942 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| GJE15_RS09450 | 1873081..1873455 | + | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| GJE15_RS09455 | 1873459..1874331 | + | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| GJE15_RS09460 | 1874344..1874685 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1874713..1874947 | - | 235 | - | - | Antitoxin |
| - | 1874843..1874946 | + | 104 | - | - | Toxin |
| GJE15_RS09465 | 1875078..1876154 | - | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| GJE15_RS09470 | 1876191..1876436 | - | 246 | Protein_1875 | IS1 family transposase | - |
| GJE15_RS09480 | 1877770..1878224 | - | 455 | Protein_1877 | IS1-like element IS1A family transposase | - |
| GJE15_RS09485 | 1878253..1878513 | - | 261 | WP_077447296.1 | excisionase | - |
| GJE15_RS09490 | 1878658..1879814 | + | 1157 | WP_087879964.1 | IS3-like element IS600 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1869211..1903108 | 33897 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T143044 NZ_CP045932:1874843-1874946 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT143044 NZ_CP045932:c1874947-1874713 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
