Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1662475..1663037 Replicon chromosome
Accession NZ_CP045871
Organism Litoricola lipolytica strain IMCC 1097

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GH975_RS08370 Protein ID WP_153714087.1
Coordinates 1662723..1663037 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GH975_RS08365 Protein ID WP_153714086.1
Coordinates 1662475..1662723 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH975_RS08340 1657984..1658604 - 621 WP_153714081.1 LysE family translocator -
GH975_RS08345 1658601..1659809 - 1209 WP_153714082.1 MFS transporter -
GH975_RS08350 1659806..1660255 - 450 WP_153714083.1 YaiI/YqxD family protein -
GH975_RS08355 1660321..1660539 - 219 WP_153714084.1 hypothetical protein -
GH975_RS08360 1660850..1662286 - 1437 WP_153714085.1 recombinase family protein -
GH975_RS08365 1662475..1662723 + 249 WP_153714086.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GH975_RS08370 1662723..1663037 + 315 WP_153714087.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GH975_RS08375 1663789..1664475 - 687 WP_153714088.1 serine protease -
GH975_RS08380 1664518..1665495 - 978 WP_153714089.1 DUF4935 domain-containing protein -
GH975_RS08385 1665591..1666019 - 429 WP_153714090.1 LacI family transcriptional regulator -
GH975_RS08390 1666016..1667371 - 1356 WP_153714091.1 recombinase family protein -
GH975_RS08395 1667368..1667859 - 492 WP_153714092.1 DUF2924 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1648641..1706068 57427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-96)

Antitoxin

Antitoxin ParD

(3-81)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12226.93 Da        Isoelectric Point: 9.6569

>T142952 WP_153714087.1 NZ_CP045871:1662723-1663037 [Litoricola lipolytica]
MSKKTVRRVRVTPRAQDDLKNIGRYTERTWGKAQRNLYLKSLETRFKWLADNPLLGRHRTDICEGYYSFPEGQHVVFYLI
GSETLDIIGIPHKDMDTISYFSES

Download         Length: 315 bp

>T142952 NZ_CP060914:513156-513431 [Escherichia coli]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATAGTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8977.92 Da        Isoelectric Point: 4.4791

>AT142952 WP_153714086.1 NZ_CP045871:1662475-1662723 [Litoricola lipolytica]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRAHLSEGASQAKNGNFVDDFSMDSLIADLDA
ES

Download         Length: 249 bp

>AT142952 NZ_CP060914:513428-513787 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCAGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References