Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 134990..135528 Replicon plasmid unnamed2
Accession NZ_CP045629
Organism Roseibium aggregatum strain ZYF703

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GFK88_RS29715 Protein ID WP_075282926.1
Coordinates 134990..135283 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GFK88_RS29720 Protein ID WP_075282925.1
Coordinates 135280..135528 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFK88_RS29700 (GFK88_29550) 132510..132812 + 303 WP_228873439.1 TraC family protein -
GFK88_RS29705 (GFK88_29555) 132841..133047 + 207 Protein_130 conjugal transfer protein TraD -
GFK88_RS29710 (GFK88_29560) 133037..134956 + 1920 WP_228873441.1 Ti-type conjugative transfer system protein TraG -
GFK88_RS29715 (GFK88_29565) 134990..135283 - 294 WP_075282926.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GFK88_RS29720 (GFK88_29570) 135280..135528 - 249 WP_075282925.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GFK88_RS29725 135774..135938 - 165 WP_168693765.1 hypothetical protein -
GFK88_RS29730 (GFK88_29575) 136302..136562 + 261 WP_075282948.1 WGR domain-containing protein -
GFK88_RS29735 (GFK88_29580) 136651..136968 - 318 WP_075282947.1 DUF736 domain-containing protein -
GFK88_RS29740 (GFK88_29585) 137690..138619 - 930 WP_228873443.1 zincin-like metallopeptidase domain-containing protein -
GFK88_RS29745 (GFK88_29590) 138892..139078 - 187 Protein_138 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..170249 170249


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11307.91 Da        Isoelectric Point: 6.9776

>T142211 WP_075282926.1 NZ_CP045629:c135283-134990 [Roseibium aggregatum]
MKVLVFSPAAKMDLEHIWDHSVEIWGLDQADRYLDEIRDACFGLASGDRRGRPVDVRAGYLKYATGVHMVYFRDHVDRLE
VIRILHQRQDVSRNLPT

Download         Length: 294 bp

>T142211 NZ_CP060459:32535-32936 [Xanthomonas citri pv. citri]
ATGAAGCGGTACATGCTTGATACCAACACCGTGAGCCATCTCGTCAAGAGCCATCCGGCTGTCTCTCGACGGGTCATTGA
AGTGCCTATGACTGCGCTATGTATGTCCGCAATTACCGGTGGGGAGCTGATGTTCGGCTTGGCTAAGGTGCCAGACGCCA
AACGCCTTCAGCAAGCCGTCATGGAACTCCTGCGGCGCGTGGATGTGCTGCCTTGGGATGGCGCGGTAATGGAGCGTTAC
GGAAGCGTAAGAGCGGACCTAGAAAAGCAAGGTAAAGCGCTTGGGTCGCTCGACATGCTTATCGCAGCACATGCACTGGA
AACGGATTCTGTCCTCGTTACCAATGACGCCGCATTTAGTCGTGTTGTTGGTTTGACCGTGGAAGATTGGACACGCAGCT
AA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9159.14 Da        Isoelectric Point: 5.7065

>AT142211 WP_075282925.1 NZ_CP045629:c135528-135280 [Roseibium aggregatum]
MARNTSVTLGDHFTGFISDQVQTGRYGSASDVVRAGLRLLEEHEAKVKALQDALIAGERSGEPQPFDFDEFKARKRAEYE
SR

Download         Length: 249 bp

>AT142211 NZ_CP060459:32278-32538 [Xanthomonas citri pv. citri]
GTGAGCCAAGTTGCCAAGCTGTTCATCAATGGCCGCAGCCAGGCAGTCCGCTTGCCTGCCGCCTATCGCTTTACCGAGAA
AGAGGTTTTCATTCGCCAAGACCCGGAGACCGGTGACGTCATCCTGTCTCGGAAGCCTGCAACGTGGGAGGACTTCTTTA
TCGCACTCAAGAGCGCAGATGTGCCTGCTAATTTTCTAGATGCCGCCGAGCGCAATCAGGGCACGCAGGACCGTGATCCT
TTTGCGGGATGGCGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References