Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4402664..4403903 Replicon chromosome
Accession NZ_CP045627
Organism Roseibium aggregatum strain ZYF703

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFK88_RS20270 Protein ID WP_228872817.1
Coordinates 4403283..4403903 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFK88_RS20265 Protein ID WP_228868887.1
Coordinates 4402664..4403233 (+) Length 190 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFK88_RS20245 (GFK88_20150) 4398713..4399561 - 849 WP_023000192.1 phosphonate ABC transporter, permease protein PhnE -
GFK88_RS20250 (GFK88_20155) 4399744..4400658 - 915 WP_023000193.1 phosphonate ABC transporter substrate-binding protein -
GFK88_RS20255 (GFK88_20160) 4400717..4401550 - 834 WP_055659582.1 phosphonate ABC transporter ATP-binding protein -
GFK88_RS20260 (GFK88_20165) 4401950..4402576 + 627 WP_228868886.1 DapH/DapD/GlmU-related protein -
GFK88_RS20265 (GFK88_20170) 4402664..4403233 + 570 WP_228868887.1 helix-turn-helix transcriptional regulator Antitoxin
GFK88_RS20270 (GFK88_20175) 4403283..4403903 + 621 WP_228872817.1 HD domain-containing protein Toxin
GFK88_RS20275 (GFK88_20180) 4404042..4404413 + 372 WP_023000198.1 STAS/SEC14 domain-containing protein -
GFK88_RS20280 (GFK88_20185) 4404498..4405286 - 789 WP_023000199.1 class II glutamine amidotransferase -
GFK88_RS20285 (GFK88_20190) 4405303..4406769 - 1467 WP_152507042.1 aminotransferase class V-fold PLP-dependent enzyme -
GFK88_RS20290 (GFK88_20195) 4406874..4407335 + 462 WP_023000201.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(28-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23114.26 Da        Isoelectric Point: 4.6255

>T142210 WP_228872817.1 NZ_CP045627:4403283-4403903 [Roseibium aggregatum]
MTKTPPSLDLPEISHTRLTGLLDFFQAAEQLKDTLRSGTTTGGRPESTAEHSWRLALMVLLFEPELKEVDLLKLLKLTLV
HDLGEAISGDVPAPLQTPGDDRQERERRDFLTLCEPLPGDVSGELSSLWDEYAAARTVEARLAKAFDKLETMLQHVLMPR
QAPSFYEFNLGYGRDRTDCSALTRQLREEVDELTRTMMTGAGREIA

Download         Length: 621 bp

>T142210 NZ_CP060459:c7569-7237 [Xanthomonas citri pv. citri]
ATGGATCGCGGCGATGTCTATTTGGTTTCGCTCGATCCCACGTCCGGCCATGAACAACAGGGCACGCGCCCGGTGCTGAT
TGTGTCGCCAAGCGCGTTCAACCGCCTGACGAAAACACCGGTCGTGCTGCCGATCACCAGTGGGGGTAACTTCGCCCGCA
CGGCAGGCTTTACCGTGTCGCTCATGGGTGCGGGTACCAACACAACTGGCGTAGTTCGCTGCGATCAGCCCCGCGCTCTC
GATCTAGCCTCGCGGCGCGCGCGCAAGCTGGAAACCGTGCCGTCCCCGATCATGGATGAGGTATTAGCGAAGCTGAGCGC
GATCCTTGAGTAA

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 21687.70 Da        Isoelectric Point: 7.9096

>AT142210 WP_228868887.1 NZ_CP045627:4402664-4403233 [Roseibium aggregatum]
MQTETAVLESSLGPSLRRWRVLNRVKQEALAYELGVSQTRISRWESGKLQPDDSNRAKITRLLRARPESAADKALLDLVS
RSAVPVHLVCDLTHRLLAMSVPRACEWRAPVNEFLNRPLWRFASEGIRATEHRLTDYGWFEPDAPDIVYRTEHVDFPEMT
IPESTIRISRLPLSDGRFARLVREEQDAA

Download         Length: 570 bp

>AT142210 NZ_CP060459:c7826-7569 [Xanthomonas citri pv. citri]
ATGCATACGACCAATCTGCGTAAGGTCGGTGGCTCGATCATGTTGGCTGTCCCGCCCGCCATTCTGGATATGCTGCGTCT
GCGTGCCGGCGCTACCGTTGGCTTGGCCGTCGATCATGGTCGCCTGGTGATCGAACCCACGCTGCGTCCGTACTACAGCC
TGGATGAGCTGCTGGCCCAATGCGACGCATCCGCCGAACTCTCCACCGAAGATCGGGAATGGCTCGACGCCAAGCCTGTT
GGCAGCGAGCTGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References