Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1300532..1300766 | Replicon | chromosome |
| Accession | NZ_CP045524 | ||
| Organism | Shigella sonnei strain 6904.27 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1300533..1300636 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1300532..1300766 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GE168_RS06680 | 1296975..1297235 | + | 261 | WP_077447296.1 | excisionase | - |
| GE168_RS06685 | 1297264..1297718 | + | 455 | Protein_1311 | IS1-like element IS1A family transposase | - |
| GE168_RS06690 | 1297813..1299042 | + | 1230 | WP_086558215.1 | IS3-like element IS2 family transposase | - |
| GE168_RS06695 | 1299053..1299298 | + | 246 | Protein_1313 | IS1 family transposase | - |
| GE168_RS06700 | 1299335..1300411 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1300532..1300766 | + | 235 | - | - | Antitoxin |
| - | 1300533..1300636 | - | 104 | - | - | Toxin |
| GE168_RS06705 | 1300794..1301135 | - | 342 | WP_000976476.1 | YebY family protein | - |
| GE168_RS06710 | 1301148..1302020 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| GE168_RS06715 | 1302024..1302398 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| GE168_RS06720 | 1302537..1302767 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| GE168_RS06725 | 1302869..1303525 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| GE168_RS06730 | 1303549..1304211 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1278811..1304211 | 25400 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T142057 NZ_CP045524:c1300636-1300533 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT142057 NZ_CP045524:1300532-1300766 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
