Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 214549..215047 Replicon plasmid pTHAF64_b
Accession NZ_CP045357
Organism Vibrio sp. THAF64

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FIU99_RS25775 Protein ID WP_152472926.1
Coordinates 214549..214728 (-) Length 60 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FIU99_RS25780 Protein ID WP_152472736.1
Coordinates 214823..215047 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU99_RS25760 210793..212886 + 2094 WP_152472732.1 TonB-dependent siderophore receptor -
FIU99_RS25765 212951..213223 + 273 WP_152472733.1 hypothetical protein -
FIU99_RS25770 213355..214323 + 969 WP_152472734.1 hypothetical protein -
FIU99_RS25775 214549..214728 - 180 WP_152472926.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FIU99_RS25780 214823..215047 - 225 WP_152472736.1 damage-inducible protein J Antitoxin
FIU99_RS25785 215301..216380 - 1080 WP_152472738.1 HNH endonuclease -
FIU99_RS25790 216425..217132 - 708 WP_152472740.1 OmpA family protein -
FIU99_RS25795 217143..218588 - 1446 WP_154351837.1 hypothetical protein -
FIU99_RS25800 219356..220036 + 681 WP_152472927.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..396761 396761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-55)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6766.98 Da        Isoelectric Point: 9.2052

>T141744 WP_152472926.1 NZ_CP045357:c214728-214549 [Vibrio sp. THAF64]
IIEARVENLLEQPHMGVQRDGIRGRLLNTPKISMMVSYCESDTIHIMRVLHQKQKLPAA

Download         Length: 180 bp

>T141744 NZ_CP060075:3759393-3759935 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8613.85 Da        Isoelectric Point: 9.2860

>AT141744 WP_152472736.1 NZ_CP045357:c215047-214823 [Vibrio sp. THAF64]
MDTRIPFGIDDETKRLAQQLADQKRKALFHDARLTEQVNLAFEKFDSKKVTFVDHESAKSCMAERKAKICNRDK

Download         Length: 225 bp

>AT141744 NZ_CP060075:3759098-3759409 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References