Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1021861..1022132 Replicon chromosome
Accession NZ_CP044313
Organism Escherichia coli strain RM11911

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1021899..1022002 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1021861..1022132 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F7D04_RS05295 1019018..1020457 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
F7D04_RS05300 1020575..1020811 + 237 WP_001295499.1 DUF1480 family protein -
F7D04_RS05305 1020916..1021107 + 192 WP_001296140.1 YebW family protein -
F7D04_RS05310 1021108..1021764 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1021861..1022132 + 272 - - Antitoxin
- 1021899..1022002 - 104 - - Toxin
F7D04_RS05315 1022160..1022501 - 342 WP_000976492.1 YebY family protein -
F7D04_RS05320 1022514..1023386 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
F7D04_RS05325 1023390..1023764 - 375 WP_000204699.1 CopC domain-containing protein YobA -
F7D04_RS05330 1023903..1024133 + 231 WP_000916763.1 DNA polymerase III subunit theta -
F7D04_RS05335 1024235..1024891 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
F7D04_RS05340 1024915..1025577 + 663 WP_050939619.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T140611 NZ_CP044313:c1022002-1021899 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT140611 NZ_CP044313:1021861-1022132 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References