Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2121516..2121787 Replicon chromosome
Accession NZ_CP043821
Organism Escherichia coli strain RM10740

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2121554..2121657 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2121516..2121787 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1748_RS10455 2117897..2119335 + 1439 Protein_2045 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
F1748_RS10460 2119453..2119689 + 237 WP_001295499.1 YebV family protein -
F1748_RS10465 2119794..2119985 + 192 WP_001296140.1 YebW family protein -
F1748_RS10475 2120775..2121419 - 645 WP_089515817.1 protein-serine/threonine phosphatase -
- 2121516..2121787 + 272 - - Antitoxin
- 2121554..2121657 - 104 - - Toxin
F1748_RS10480 2121815..2122156 - 342 WP_000976492.1 YebY family protein -
F1748_RS10485 2122169..2123041 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
F1748_RS10490 2123045..2123419 - 375 WP_000204699.1 CopC domain-containing protein YobA -
F1748_RS10495 2123558..2123788 + 231 WP_000916763.1 DNA polymerase III subunit theta -
F1748_RS10500 2123890..2124546 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
F1748_RS10505 2124570..2125232 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2104901..2127289 22388


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T139266 NZ_CP043821:c2121657-2121554 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT139266 NZ_CP043821:2121516-2121787 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References