Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2212152..2212420 Replicon chromosome
Accession NZ_CP043414
Organism Escherichia coli strain EC42405

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2212279..2212382 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2212152..2212420 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZN31_RS10485 2208705..2209367 - 663 WP_000944256.1 exodeoxyribonuclease X -
FZN31_RS10490 2209391..2210047 - 657 WP_032184416.1 carbon-nitrogen hydrolase family protein -
FZN31_RS10495 2210149..2210379 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FZN31_RS10500 2210518..2210892 + 375 WP_000204701.1 CopC domain-containing protein YobA -
FZN31_RS10505 2210896..2211768 + 873 WP_000879324.1 copper homeostasis membrane protein CopD -
FZN31_RS10510 2211781..2212122 + 342 WP_000976467.1 YebY family protein -
- 2212152..2212420 - 269 - - Antitoxin
- 2212279..2212382 + 104 - - Toxin
FZN31_RS10515 2212517..2213173 + 657 WP_000812737.1 protein-serine/threonine phosphatase -
FZN31_RS10520 2213174..2213365 - 192 WP_001296140.1 YebW family protein -
FZN31_RS10525 2213470..2213706 - 237 WP_001295499.1 DUF1480 family protein -
FZN31_RS10530 2213824..2215263 - 1440 WP_105287968.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T138723 NZ_CP043414:2212279-2212382 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT138723 NZ_CP043414:c2212420-2212152 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGATGGTCATCAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References