Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2056991..2057262 Replicon chromosome
Accession NZ_CP043334
Organism Escherichia coli strain WCHEC115106

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2057121..2057224 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2056991..2057262 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZC46_RS09960 2053546..2054208 - 663 WP_000944256.1 exodeoxyribonuclease X -
FZC46_RS09965 2054232..2054888 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
FZC46_RS09970 2054990..2055220 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FZC46_RS09975 2055359..2055733 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FZC46_RS09980 2055737..2056609 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
FZC46_RS09985 2056622..2056963 + 342 WP_000976492.1 YebY family protein -
- 2056991..2057262 - 272 - - Antitoxin
- 2057121..2057224 + 104 - - Toxin
FZC46_RS09990 2057359..2058015 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FZC46_RS09995 2058016..2058207 - 192 WP_001296140.1 YebW family protein -
FZC46_RS10000 2058312..2058548 - 237 WP_001295499.1 YebV family protein -
FZC46_RS10005 2058666..2060105 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T138380 NZ_CP043334:2057121-2057224 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT138380 NZ_CP043334:c2057262-2056991 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References