Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2248049..2248320 Replicon chromosome
Accession NZ_CP043195
Organism Escherichia coli O16:H48 strain PG20180062

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2248179..2248282 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2248049..2248320 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYA13_RS10725 2244604..2245266 - 663 WP_000944256.1 exodeoxyribonuclease X -
FYA13_RS10730 2245290..2245946 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FYA13_RS10735 2246048..2246278 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FYA13_RS10740 2246417..2246791 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FYA13_RS10745 2246795..2247667 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FYA13_RS10750 2247680..2248021 + 342 WP_000976476.1 YebY family protein -
- 2248049..2248320 - 272 - - Antitoxin
- 2248179..2248282 + 104 - - Toxin
FYA13_RS10755 2248417..2249073 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FYA13_RS10760 2249074..2249265 - 192 WP_000457842.1 YebW family protein -
FYA13_RS10765 2249370..2249606 - 237 WP_001295499.1 DUF1480 family protein -
FYA13_RS10770 2249724..2251163 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T137594 NZ_CP043195:2248179-2248282 [Escherichia coli O16:H48]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT137594 NZ_CP043195:c2248320-2248049 [Escherichia coli O16:H48]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References