Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 113230..113729 Replicon chromosome
Accession NZ_CP042325
Organism Corynebacterium sp. sy039

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FQV43_RS00510 Protein ID WP_146338111.1
Coordinates 113472..113729 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FQV43_RS00505 Protein ID WP_144273631.1
Coordinates 113230..113475 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQV43_RS00480 109055..109705 + 651 WP_168194998.1 TetR/AcrR family transcriptional regulator -
FQV43_RS00485 109833..110039 - 207 WP_146338102.1 hypothetical protein -
FQV43_RS00490 110321..111334 + 1014 WP_146338105.1 FtsX-like permease family protein -
FQV43_RS00495 111331..112425 + 1095 WP_146338107.1 hypothetical protein -
FQV43_RS00500 112422..113078 + 657 WP_146338109.1 ABC transporter ATP-binding protein -
FQV43_RS00505 113230..113475 + 246 WP_144273631.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FQV43_RS00510 113472..113729 + 258 WP_146338111.1 Txe/YoeB family addiction module toxin Toxin
FQV43_RS00515 113911..115140 + 1230 WP_146338113.1 ATP-binding protein -
FQV43_RS00520 115274..116524 + 1251 WP_146338115.1 multidrug effflux MFS transporter -
FQV43_RS00525 116544..116780 - 237 WP_146338117.1 hypothetical protein -
FQV43_RS00530 117011..118219 + 1209 WP_146338119.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10047.59 Da        Isoelectric Point: 9.6560

>T135394 WP_146338111.1 NZ_CP042325:113472-113729 [Corynebacterium sp. sy039]
MRLVFTPNGWADYTFWLKADRQILKRINRLIDDVLRDPTSGIGKPEPLRHMLAGAWSRRITDEHRLVYLVDADDVVILQA
RFHYN

Download         Length: 258 bp

>T135394 NZ_CP042325:113472-113729 [Corynebacterium sp. sy039]
ATGAGACTTGTTTTTACTCCTAATGGGTGGGCTGATTATACGTTCTGGCTGAAGGCTGATAGGCAAATACTGAAGCGGAT
TAATCGGTTGATTGACGATGTGCTTCGTGACCCTACCTCGGGTATCGGCAAGCCTGAACCGCTTCGCCATATGCTTGCGG
GTGCATGGTCACGACGGATTACGGATGAACATCGGTTGGTTTATCTCGTTGATGCCGACGATGTTGTTATACTCCAAGCG
CGTTTCCACTACAACTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9135.20 Da        Isoelectric Point: 4.5659

>AT135394 WP_144273631.1 NZ_CP042325:113230-113475 [Corynebacterium sp. sy039]
MAITATEARKNLFPLIQQVNDDRNPVEITSRNGDAVLISRADYESLEETAYLLRVPANAQHLLESLAQARAGQYEEHDLI
R

Download         Length: 246 bp

>AT135394 NZ_CP042325:113230-113475 [Corynebacterium sp. sy039]
ATGGCTATCACTGCAACTGAAGCGCGCAAGAATTTGTTTCCACTTATTCAACAAGTGAATGATGATCGAAACCCCGTGGA
GATTACTTCTCGGAATGGGGATGCTGTTCTCATTTCACGTGCCGATTATGAATCCCTAGAGGAAACGGCATATCTTCTCC
GTGTTCCTGCAAATGCTCAGCATTTGCTTGAGTCTCTTGCGCAGGCTCGTGCTGGTCAGTACGAGGAACATGATCTGATC
CGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References