Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2763590..2763821 Replicon chromosome
Accession NZ_CP042250
Organism Escherichia coli strain BCE049

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2763591..2763693 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2763590..2763821 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQU84_RS15600 2760502..2761590 + 1089 WP_047088016.1 recombinase RecT -
FQU84_RS15605 2761654..2761848 + 195 WP_021500490.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
FQU84_RS15610 2761841..2762029 + 189 WP_047087971.1 DUF1187 family protein -
- 2761847..2762025 - 179 NuclAT_0 - -
- 2761847..2762025 - 179 NuclAT_0 - -
- 2761847..2762025 - 179 NuclAT_0 - -
- 2761847..2762025 - 179 NuclAT_0 - -
FQU84_RS15615 2762136..2762417 + 282 WP_001311878.1 excisionase -
FQU84_RS15620 2762383..2763459 + 1077 WP_047087972.1 phage integrase Arm DNA-binding domain-containing protein -
- 2763590..2763821 + 232 - - Antitoxin
- 2763591..2763693 - 103 - - Toxin
FQU84_RS15625 2763851..2764192 - 342 WP_000984819.1 YebY family protein -
FQU84_RS15630 2764205..2765077 - 873 WP_000879320.1 copper homeostasis membrane protein CopD -
FQU84_RS15635 2765081..2765455 - 375 WP_000168747.1 CopC domain-containing protein YobA -
FQU84_RS15640 2765594..2765824 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FQU84_RS15645 2765926..2766582 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
FQU84_RS15650 2766605..2767267 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2704956..2785911 80955


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135091 NZ_CP042250:c2763693-2763591 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT135091 NZ_CP042250:2763590-2763821 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References