Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2271602..2271870 Replicon chromosome
Accession NZ_CP042246
Organism Escherichia coli strain PU-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2271730..2271832 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2271602..2271870 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQU83_RS12785 2268156..2268818 - 663 WP_000944256.1 exodeoxyribonuclease X -
FQU83_RS12790 2268841..2269497 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
FQU83_RS12795 2269599..2269829 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FQU83_RS12800 2269968..2270342 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FQU83_RS12805 2270346..2271218 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
FQU83_RS12810 2271231..2271572 + 342 WP_000984819.1 YebY family protein -
- 2271602..2271870 - 269 - - Antitoxin
- 2271730..2271832 + 103 - - Toxin
FQU83_RS12815 2271967..2272623 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
FQU83_RS12820 2272624..2272815 - 192 WP_001296140.1 YebW family protein -
FQU83_RS12825 2272920..2273156 - 237 WP_001295499.1 DUF1480 family protein -
FQU83_RS12830 2273274..2274713 - 1440 WP_101357011.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135048 NZ_CP042246:2271730-2271832 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT135048 NZ_CP042246:c2271870-2271602 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References