Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2172340..2172998 Replicon chromosome
Accession NZ_CP041778
Organism Burkholderia sp. MS455

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FPJ27_RS14450 Protein ID WP_204421568.1
Coordinates 2172340..2172774 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FPJ27_RS14455 Protein ID WP_204421569.1
Coordinates 2172771..2172998 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPJ27_RS14425 2167374..2168237 + 864 WP_204421565.1 hypothetical protein -
FPJ27_RS14430 2168797..2169567 + 771 WP_204421566.1 CDP-diacylglycerol diphosphatase -
FPJ27_RS14435 2170204..2170502 + 299 Protein_2007 integrase -
FPJ27_RS14440 2170775..2171491 - 717 WP_204421567.1 helix-turn-helix domain-containing protein -
FPJ27_RS14445 2171696..2172130 - 435 Protein_2009 IS5/IS1182 family transposase -
FPJ27_RS14450 2172340..2172774 - 435 WP_204421568.1 PIN domain-containing protein Toxin
FPJ27_RS14455 2172771..2172998 - 228 WP_204421569.1 CopG family transcriptional regulator Antitoxin
FPJ27_RS14460 2173145..2173793 + 649 Protein_2012 hypothetical protein -
FPJ27_RS14465 2173735..2173896 - 162 Protein_2013 IS110 family transposase -
FPJ27_RS14470 2173892..2174023 - 132 Protein_2014 transposase -
FPJ27_RS14475 2174488..2175219 - 732 Protein_2015 IS110 family transposase -
FPJ27_RS14480 2175260..2176489 - 1230 WP_204423208.1 IS256 family transposase -
FPJ27_RS14485 2176646..2176960 - 315 Protein_2017 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - pilW 2097416..2280338 182922


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15715.08 Da        Isoelectric Point: 7.2342

>T129238 WP_204421568.1 NZ_CP041778:c2172774-2172340 [Burkholderia sp. MS455]
MMTYLLDVNVLIALLDPAHVQHEPAHAWFGRVGHSAWSTCPLTENGVLRIIGNPKYPNTMGSPASVAPLVAQLRAHAGHT
FWPDDVSLLDEKHVDATRLLSSAQLTDTYLLALARAHKGKLATFDRRLVVDAVPNGAKHLELIS

Download         Length: 435 bp

>T129238 NZ_CP041778:c2172774-2172340 [Burkholderia sp. MS455]
TTGATGACCTACCTGCTCGACGTCAACGTTCTTATCGCGCTGCTGGATCCTGCCCATGTTCAGCACGAGCCGGCACATGC
ATGGTTTGGCCGAGTAGGGCATTCCGCATGGTCGACTTGCCCACTGACCGAGAACGGCGTGCTGCGGATTATCGGTAATC
CGAAGTATCCGAACACGATGGGTTCGCCGGCCTCCGTCGCCCCGCTCGTCGCGCAACTGCGGGCGCACGCCGGGCACACT
TTCTGGCCGGATGATGTGAGCTTGCTGGACGAAAAGCACGTCGACGCCACGCGCTTGCTGTCGTCGGCGCAGCTGACGGA
CACGTACTTGCTGGCGCTGGCGCGCGCACACAAGGGCAAGCTGGCGACCTTCGATCGACGCTTGGTTGTCGACGCCGTGC
CGAATGGCGCCAAGCATCTTGAACTAATTTCCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8181.25 Da        Isoelectric Point: 8.9793

>AT129238 WP_204421569.1 NZ_CP041778:c2172998-2172771 [Burkholderia sp. MS455]
MRTTIDIDDDVLAFARERAKPGTSIGKVISELARAALQRTTTNQTSRNGLPLMPSSATNRPVTLDVVNQLRDDSL

Download         Length: 228 bp

>AT129238 NZ_CP041778:c2172998-2172771 [Burkholderia sp. MS455]
ATGCGTACCACTATCGACATCGATGACGACGTCCTCGCCTTCGCACGGGAGCGTGCGAAGCCCGGCACGAGTATCGGCAA
GGTCATTTCGGAGCTCGCGCGCGCCGCATTGCAACGCACGACGACCAACCAGACGAGCCGCAACGGGCTGCCGTTGATGC
CGTCCTCCGCGACGAACCGTCCGGTCACGCTCGACGTCGTTAATCAACTTCGTGACGATTCACTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References