Detailed information of TA system TA129185

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2677830..2678155
• Replicon: chromosome
• Accession: NZ_CP041757
• Organism: Bacillus sp. KBS0812

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: FFE90_RS14200
• Protein ID: WP_004398662.1
• Coordinates: 2677830..2678009 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2677933..2678155 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFE90_RS14190	2677056..2677193	-	138	WP_003229934.1	hypothetical protein	-
FFE90_RS14195	2677235..2677684	-	450	WP_003229933.1	phage portal protein	-
FFE90_RS14200	2677830..2678009	+	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2677933..2678155	-	223	NuclAT_0	-	Antitoxin
-	2677933..2678155	-	223	NuclAT_0	-	Antitoxin
-	2677933..2678155	-	223	NuclAT_0	-	Antitoxin
-	2677933..2678155	-	223	NuclAT_0	-	Antitoxin
FFE90_RS14205	2678389..2678478	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
FFE90_RS14210	2678732..2679175	-	444	WP_003229930.1	phage tail tube protein	-
FFE90_RS14215	2679178..2680578	-	1401	WP_003229929.1	phage tail sheath family protein	-
FFE90_RS14220	2680579..2680770	-	192	WP_010886574.1	hypothetical protein	-
FFE90_RS14225	2680767..2681204	-	438	WP_003229927.1	hypothetical protein	-
FFE90_RS14230	2681217..2681720	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
FFE90_RS14235	2681717..2682079	-	363	WP_003229925.1	YqbH/XkdH family protein	-
FFE90_RS14240	2682076..2682471	-	396	WP_004398566.1	DUF3199 family protein	-
FFE90_RS14245	2682475..2682786	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2647343..2698833	51490

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T129185 WP_004398662.1 NZ_CP041757:2677830-2678009 [Bacillus sp. KBS0812]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T129185 NZ_CP041757:2677830-2678009 [Bacillus sp. KBS0812]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT129185 NZ_CP041757:c2678155-2677933 [Bacillus sp. KBS0812]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin