Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1569778..1570418 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNU76_RS07005 Protein ID WP_144277522.1
Coordinates 1570029..1570418 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNU76_RS07000 Protein ID WP_144277521.1
Coordinates 1569778..1570035 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS06980 1565445..1566878 + 1434 WP_144277517.1 YdiU family protein -
FNU76_RS06985 1566827..1567204 - 378 WP_144277518.1 hypothetical protein -
FNU76_RS06990 1567491..1568219 + 729 WP_144277519.1 transporter substrate-binding domain-containing protein -
FNU76_RS06995 1568387..1569493 + 1107 WP_144277520.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
FNU76_RS07000 1569778..1570035 + 258 WP_144277521.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FNU76_RS07005 1570029..1570418 + 390 WP_144277522.1 type II toxin-antitoxin system VapC family toxin Toxin
FNU76_RS07010 1570597..1571442 + 846 WP_144277523.1 S-formylglutathione hydrolase -
FNU76_RS07015 1571439..1572923 - 1485 WP_144277524.1 PLP-dependent aminotransferase family protein -
FNU76_RS07020 1573010..1573633 + 624 WP_144277525.1 pyridoxamine 5'-phosphate oxidase family protein -
FNU76_RS07025 1573732..1574925 + 1194 WP_144277526.1 CoA transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14449.66 Da        Isoelectric Point: 6.0856

>T129057 WP_144277522.1 NZ_CP041730:1570029-1570418 [Chitinimonas arctica]
MVIDTSAVLAWLKQEPERERIITALEVHKVCRISAVSLLEAHIVVRAREHPTMLGKLQRFLEEIGATVTPFDERQARLAD
VAFLRYGKGQGHPAQLNFGDCAVYALSKSLDEPLLFVGNDFSQTDIEKC

Download         Length: 390 bp

>T129057 NZ_CP041730:1570029-1570418 [Chitinimonas arctica]
ATGGTAATCGATACGTCGGCTGTGCTGGCCTGGCTCAAGCAGGAGCCAGAGCGTGAGCGCATCATCACCGCTCTGGAGGT
GCACAAAGTCTGCCGCATTTCGGCGGTCAGTCTGCTGGAAGCGCATATCGTAGTCAGGGCGCGCGAGCACCCGACCATGC
TGGGAAAACTGCAGCGCTTCCTGGAGGAAATAGGTGCCACTGTGACGCCCTTCGACGAGCGCCAAGCCCGCCTCGCCGAC
GTAGCCTTCCTTCGCTATGGCAAAGGGCAAGGCCATCCGGCCCAACTAAATTTCGGCGACTGCGCGGTATATGCCTTATC
CAAGTCGCTGGACGAACCCTTGTTATTTGTTGGCAACGACTTCTCGCAAACGGACATCGAGAAATGTTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9273.56 Da        Isoelectric Point: 5.0893

>AT129057 WP_144277521.1 NZ_CP041730:1569778-1570035 [Chitinimonas arctica]
MAIVIEDLQLERLAQQIATAEGVSVTEVVREGLMSLAGLRGLPAKKPALRERLTALAREVDAVPHRPSDGRSDNDILGYN
EHGTW

Download         Length: 258 bp

>AT129057 NZ_CP041730:1569778-1570035 [Chitinimonas arctica]
ATGGCTATCGTCATCGAAGACCTACAACTGGAACGGCTAGCGCAGCAGATCGCTACTGCCGAGGGCGTGAGCGTCACAGA
AGTTGTTCGCGAGGGATTGATGTCCCTGGCGGGTTTGCGTGGGCTGCCGGCGAAAAAGCCCGCGCTCCGGGAACGGCTGA
CCGCGCTGGCGAGGGAAGTCGATGCGGTCCCGCATCGACCTAGCGATGGCCGTAGCGACAACGACATTCTGGGTTACAAC
GAGCACGGCACATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References