Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 3090489..3091092 Replicon chromosome
Accession NZ_CP041660
Organism Catenovulum sediminis strain WS1-A

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FNT16_RS13055 Protein ID WP_143871991.1
Coordinates 3090489..3090809 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FNT16_RS13060 Protein ID WP_143871992.1
Coordinates 3090802..3091092 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNT16_RS13035 3086218..3088515 + 2298 WP_143871987.1 hypothetical protein -
FNT16_RS13040 3088518..3089396 + 879 WP_143871988.1 hypothetical protein -
FNT16_RS13045 3089383..3090057 - 675 WP_143871989.1 deoxyribonuclease V -
FNT16_RS13050 3090235..3090447 + 213 WP_143871990.1 tyrosine-type recombinase/integrase -
FNT16_RS13055 3090489..3090809 + 321 WP_143871991.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNT16_RS13060 3090802..3091092 + 291 WP_143871992.1 helix-turn-helix domain-containing protein Antitoxin
FNT16_RS13065 3091613..3092977 + 1365 WP_143871993.1 hypothetical protein -
FNT16_RS13070 3093102..3093593 + 492 WP_143871994.1 hypothetical protein -
FNT16_RS13075 3093705..3094133 + 429 WP_143871995.1 hypothetical protein -
FNT16_RS13080 3094471..3094812 - 342 WP_143871996.1 hypothetical protein -
FNT16_RS13085 3094743..3095327 - 585 WP_143871997.1 ATP-binding protein -
FNT16_RS13090 3095320..3095994 - 675 WP_143871998.1 transposase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(3-101)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12288.20 Da        Isoelectric Point: 7.0106

>T128952 WP_143871991.1 NZ_CP041660:3090489-3090809 [Catenovulum sediminis]
MVIIETAVFTKIIKTLMTDDEYKNLQEALITRPDRGAIIKNSNGIRKIRWTLEGSGKSGGVRVIYYWMTEDEQIYMLYAY
PKSAQENLTDAQLKVMKQIVEGWTHE

Download         Length: 321 bp

>T128952 NZ_CP041660:3090489-3090809 [Catenovulum sediminis]
ATGGTTATAATAGAAACGGCCGTATTCACCAAAATCATAAAAACCTTAATGACAGATGATGAATACAAAAACTTACAAGA
AGCCCTAATCACTAGGCCAGATAGAGGGGCGATAATAAAAAATAGCAACGGGATCAGAAAAATCCGCTGGACACTTGAAG
GTAGTGGAAAAAGTGGAGGCGTACGGGTTATCTATTATTGGATGACTGAAGATGAGCAGATATACATGCTGTACGCGTAC
CCAAAAAGTGCACAAGAAAATTTAACCGATGCCCAATTAAAAGTCATGAAACAGATAGTAGAGGGGTGGACACATGAATG
A

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10662.31 Da        Isoelectric Point: 10.3403

>AT128952 WP_143871992.1 NZ_CP041660:3090802-3091092 [Catenovulum sediminis]
MNDEMFKELVQSMEQAGDIMKGKAKPSRVTVFAEPEVKAIRAKTGLSQSRFADIVGVSKRTLENWEQGRRHPTGPARALL
KILDADPQYALKALHG

Download         Length: 291 bp

>AT128952 NZ_CP041660:3090802-3091092 [Catenovulum sediminis]
ATGAATGATGAAATGTTTAAAGAGCTTGTTCAGAGCATGGAGCAAGCAGGCGACATAATGAAAGGTAAGGCTAAGCCATC
ACGTGTGACCGTGTTTGCAGAGCCTGAAGTTAAAGCCATAAGAGCGAAAACAGGTTTAAGCCAAAGTCGCTTTGCAGACA
TAGTAGGTGTTAGCAAACGAACGCTAGAAAACTGGGAACAAGGTCGCAGGCATCCAACAGGGCCAGCAAGAGCATTACTG
AAAATACTGGATGCTGATCCACAATATGCACTAAAAGCATTGCATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References