Detailed information of TA system TA128948

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 799547..800072
• Replicon: chromosome
• Accession: NZ_CP041660
• Organism: Catenovulum sediminis strain WS1-A

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FNT16_RS03245
• Protein ID: WP_143870196.1
• Coordinates: 799788..800072 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FNT16_RS03240
• Protein ID: WP_143870195.1
• Coordinates: 799547..799798 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNT16_RS03225	794949..796421	-	1473	WP_143870193.1	type I restriction-modification system subunit M	-
FNT16_RS03230	796540..799011	-	2472	WP_143870194.1	DEAD/DEAH box helicase family protein	-
FNT16_RS03240	799547..799798	+	252	WP_143870195.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FNT16_RS03245	799788..800072	+	285	WP_143870196.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FNT16_RS03250	800216..800941	-	726	WP_143870197.1	prolyl oligopeptidase family serine peptidase	-
FNT16_RS03255	801118..801552	+	435	Protein_625	SOS response-associated peptidase family protein	-
FNT16_RS03260	801625..802470	-	846	WP_143870198.1	hypothetical protein	-
FNT16_RS03265	802485..804809	-	2325	WP_143870199.1	isoamylase	-
FNT16_RS20330	804742..804915	+	174	WP_185976765.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-77)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10940.01 Da
• Isoelectric Point: 10.7742

>T128948 WP_143870196.1 NZ_CP041660:799788-800072 [Catenovulum sediminis]
MTYKLKFLPVALKEWKKLAPPIQNQFKKKLTERLENPKVPSAKLSGFDSVYKIKLRTAGYRLVYEINDNEITVLVLGVGK
RDKDKVYKTVRSRV

Nucleotide

• Length: 285 bp

>T128948 NZ_CP041660:799788-800072 [Catenovulum sediminis]
ATGACTTATAAGTTAAAGTTTTTACCCGTGGCGTTAAAAGAATGGAAAAAGCTCGCGCCACCAATTCAAAATCAGTTCAA
AAAGAAACTAACTGAGCGACTAGAAAACCCAAAAGTTCCGTCTGCAAAACTTAGCGGGTTTGATTCTGTCTATAAAATTA
AGCTTCGTACCGCTGGTTATCGTCTAGTTTACGAAATCAATGACAATGAAATTACCGTATTGGTTTTAGGTGTAGGCAAA
AGAGATAAAGATAAAGTTTATAAAACAGTTAGAAGTAGGGTTTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9202.64 Da
• Isoelectric Point: 4.4217

>AT128948 WP_143870195.1 NZ_CP041660:799547-799798 [Catenovulum sediminis]
MRQVLADCSASISELKKSPTALLNEAAGSPIAILNHNKPAAYLIPADTYEWMMEMLDDVELTKLVKERLKDKSQAIEVSL
DDL

Nucleotide

• Length: 252 bp

>AT128948 NZ_CP041660:799547-799798 [Catenovulum sediminis]
ATGAGACAAGTTTTAGCAGATTGTTCAGCCAGCATTTCGGAATTGAAAAAAAGTCCAACAGCTTTATTAAACGAGGCTGC
AGGTTCTCCAATTGCGATATTGAACCACAATAAACCAGCTGCTTATCTAATCCCAGCAGACACGTACGAATGGATGATGG
AAATGCTTGATGATGTTGAACTAACTAAATTAGTTAAAGAGCGACTAAAAGATAAATCCCAAGCGATAGAAGTATCACTG
GATGACTTATAA