Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4339853..4340124 Replicon chromosome
Accession NZ_CP041623
Organism Escherichia coli O157:H7 strain ATCC 43888

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4339891..4339994 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4339853..4340124 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNZ21_RS21795 4337010..4338449 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FNZ21_RS21800 4338567..4338803 + 237 WP_001295499.1 DUF1480 family protein -
FNZ21_RS21805 4338908..4339099 + 192 WP_001296140.1 YebW family protein -
FNZ21_RS21810 4339100..4339756 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 4339853..4340124 + 272 - - Antitoxin
- 4339891..4339994 - 104 - - Toxin
FNZ21_RS21815 4340152..4340493 - 342 WP_000976483.1 YebY family protein -
FNZ21_RS21820 4340506..4341378 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
FNZ21_RS21825 4341382..4341756 - 375 WP_000168751.1 CopC domain-containing protein YobA -
FNZ21_RS21830 4341895..4342125 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FNZ21_RS21835 4342227..4342883 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
FNZ21_RS21840 4342907..4343569 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T128825 NZ_CP041623:c4339994-4339891 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT128825 NZ_CP041623:4339853-4340124 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References