Detailed information of TA system TA127453

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 42702..43327
• Replicon: plasmid SA20143792 strain 14[5]12:i:-
• Accession: NZ_CP041027
• Organism: Salmonella enterica subsp. enterica serovar 14[5]12:i:- strain SA20143792

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FI669_RS24890
• Protein ID: WP_000911322.1
• Coordinates: 42702..43100 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FI669_RS24895
• Protein ID: WP_000450265.1
• Coordinates: 43100..43327 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FI669_RS24875	38893..39387	+	495	WP_010999946.1	entry exclusion protein	-
FI669_RS24880	39423..40154	+	732	WP_000782438.1	complement resistance protein TraT	-
FI669_RS24885	40531..42693	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
FI669_RS24890	42702..43100	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
FI669_RS24895	43100..43327	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..190723	190723

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (21-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (6-58)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T127453 WP_000911322.1 NZ_CP041027:c43100-42702 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T127453 NZ_CP041027:c43100-42702 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT127453 WP_000450265.1 NZ_CP041027:c43327-43100 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT127453 NZ_CP041027:c43327-43100 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
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