Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 669781..670379 Replicon chromosome
Accession NZ_CP041016
Organism Sphingobium fuliginis ATCC 27551

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FIL70_RS03100 Protein ID WP_140041603.1
Coordinates 669781..670080 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FIL70_RS03105 Protein ID WP_140041605.1
Coordinates 670077..670379 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIL70_RS03070 664781..665014 + 234 WP_140041593.1 conjugal transfer protein TraD -
FIL70_RS03075 665007..665594 - 588 WP_140041595.1 hypothetical protein -
FIL70_RS03080 665578..666507 - 930 WP_140041596.1 HEPN domain-containing protein -
FIL70_RS03085 666504..667121 - 618 WP_140041598.1 hypothetical protein -
FIL70_RS03090 667277..667522 + 246 WP_140041599.1 hypothetical protein -
FIL70_RS03095 667646..669382 - 1737 WP_140041601.1 ParB/RepB/Spo0J family partition protein -
FIL70_RS03100 669781..670080 - 300 WP_140041603.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FIL70_RS03105 670077..670379 - 303 WP_140041605.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FIL70_RS03110 670887..671096 + 210 WP_140041607.1 AlpA family phage regulatory protein -
FIL70_RS03115 671484..671756 - 273 WP_140041608.1 hypothetical protein -
FIL70_RS03120 672180..672620 + 441 WP_140041609.1 DUF488 domain-containing protein -
FIL70_RS03125 672640..673425 + 786 WP_140041610.1 hypothetical protein -
FIL70_RS03130 673491..674501 + 1011 WP_208759570.1 DUF3644 domain-containing protein -
FIL70_RS03135 675053..675349 + 297 WP_140041612.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-55)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11208.80 Da        Isoelectric Point: 6.4686

>T127428 WP_140041603.1 NZ_CP041016:c670080-669781 [Sphingobium fuliginis ATCC 27551]
MKLVWSRHAAADRMAIFTWIAQDDPRAAALVDDRLEDAARRLIDFPESGRPGRIEGTRELVVARTPYVVPYQIVGDTVRL
LRVIHGARMWPQEINDGDG

Download         Length: 300 bp

>T127428 NZ_CP041016:c670080-669781 [Sphingobium fuliginis ATCC 27551]
ATGAAACTGGTCTGGTCGCGACACGCGGCCGCCGATCGCATGGCCATTTTCACCTGGATCGCGCAAGACGATCCACGCGC
GGCTGCGCTTGTCGATGACCGGCTGGAGGATGCGGCACGCCGGCTCATCGACTTTCCGGAAAGTGGCCGCCCAGGCCGGA
TCGAAGGCACGAGGGAACTCGTAGTGGCCCGGACCCCCTATGTCGTTCCTTACCAGATCGTCGGAGACACGGTGCGCTTG
CTCCGCGTCATTCATGGCGCGCGCATGTGGCCGCAAGAGATAAACGACGGGGATGGTTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11252.83 Da        Isoelectric Point: 4.4821

>AT127428 WP_140041605.1 NZ_CP041016:c670379-670077 [Sphingobium fuliginis ATCC 27551]
MANNALIQTRIDADVKEQAAAVFEKMGLTVSDAVRILLTRTAREGIVPMELLVEKQAYDEWFRARVQEALDDERPDIPDE
EISATFAALREKARKGLPPQ

Download         Length: 303 bp

>AT127428 NZ_CP041016:c670379-670077 [Sphingobium fuliginis ATCC 27551]
ATGGCCAATAATGCGCTGATCCAGACGCGAATCGACGCGGACGTGAAAGAGCAAGCCGCCGCCGTCTTCGAAAAGATGGG
GCTGACCGTCTCCGACGCCGTCCGTATCCTACTCACCCGCACGGCCCGCGAGGGCATCGTCCCCATGGAACTGCTTGTAG
AGAAGCAGGCCTATGACGAATGGTTCAGGGCAAGGGTGCAGGAAGCCCTGGACGACGAACGGCCCGACATTCCCGATGAA
GAAATCTCGGCGACATTCGCGGCGCTTCGGGAAAAGGCGCGCAAGGGCCTTCCCCCGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References