Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1045499..1046034 Replicon chromosome
Accession NZ_CP040914
Organism Mesorhizobium sp. 8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGU64_RS04910 Protein ID WP_139951115.1
Coordinates 1045499..1045774 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGU64_RS04915 Protein ID WP_139951116.1
Coordinates 1045774..1046034 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGU64_RS04890 1040827..1042968 - 2142 WP_139951113.1 sodium-translocating pyrophosphatase -
FGU64_RS04895 1043224..1044438 - 1215 WP_139951114.1 MFS transporter -
FGU64_RS04900 1044435..1044929 - 495 WP_136353377.1 transcription antitermination factor NusB -
FGU64_RS04905 1044926..1045420 - 495 WP_136353375.1 6,7-dimethyl-8-ribityllumazine synthase -
FGU64_RS04910 1045499..1045774 - 276 WP_139951115.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGU64_RS04915 1045774..1046034 - 261 WP_139951116.1 ribbon-helix-helix domain-containing protein Antitoxin
FGU64_RS04920 1046107..1046724 - 618 WP_139951117.1 riboflavin synthase -
FGU64_RS04925 1046724..1047848 - 1125 WP_139951118.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
FGU64_RS04930 1047848..1048315 - 468 WP_136353368.1 transcriptional regulator NrdR -
FGU64_RS04935 1048444..1049757 - 1314 WP_139951119.1 serine hydroxymethyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10745.56 Da        Isoelectric Point: 10.5178

>T127217 WP_139951115.1 NZ_CP040914:c1045774-1045499 [Mesorhizobium sp. 8]
MELQWASKALSDLARLHAFLVPVNRKAAARAIQTLVAAPLRLLEHPRLGERLEEFEPREVRRILIGNYEMRYELRGTIVY
VLRVWHAREDR

Download         Length: 276 bp

>T127217 NZ_CP040914:c1045774-1045499 [Mesorhizobium sp. 8]
ATGGAATTGCAATGGGCGTCGAAGGCGTTGTCCGACCTTGCGCGCCTCCATGCTTTTTTGGTTCCCGTCAATCGCAAGGC
TGCCGCCCGCGCCATCCAGACTCTCGTTGCGGCGCCTTTGCGCCTTCTGGAACATCCTCGATTGGGCGAAAGGCTCGAGG
AATTCGAGCCGCGTGAAGTGCGGCGTATCCTGATCGGCAACTACGAGATGCGCTATGAATTGCGCGGCACAATAGTTTAC
GTGCTTCGCGTCTGGCACGCGCGAGAAGATCGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9698.16 Da        Isoelectric Point: 4.8668

>AT127217 WP_139951116.1 NZ_CP040914:c1046034-1045774 [Mesorhizobium sp. 8]
METKVITAHVPRPLAEKVDALAARLERPRGWIVKQALSAWVDMEEERRRMTLEALADVDVGAIIDHRVVQEWADSLDSEK
SLPAPL

Download         Length: 261 bp

>AT127217 NZ_CP040914:c1046034-1045774 [Mesorhizobium sp. 8]
ATGGAAACGAAAGTGATAACCGCGCATGTTCCGCGGCCGCTGGCCGAAAAGGTGGACGCTCTCGCCGCAAGGCTGGAGCG
ACCACGAGGCTGGATCGTCAAGCAGGCCCTCTCGGCATGGGTCGACATGGAAGAAGAGCGCCGGCGCATGACACTCGAAG
CGCTCGCCGATGTGGACGTGGGGGCTATTATCGATCATCGGGTCGTTCAGGAATGGGCGGACAGCCTCGATAGCGAGAAG
TCACTGCCGGCGCCGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References